Protein Alignment PTPRR and Ptp36E

DIOPT Version :10

• Sequence 1: NP_002840.2
• Gene: PTPRR / 5801
• HGNCID: 9680
• Length: 657
• Species: Homo sapiens
• Sequence 2: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 382
• Identity: 104/382 - (27%)
• Similarity: 170/382 - (44%)
• Gaps: 79/382 - (20%)

Human   303 VDPQGRGAPEIKATTATSVCPSPFKMKPI--GL-------QERRGSNVSLTLDMSSLG--NIEPF 356
            |:.|.|     |:....|: |:..|:..:  ||       .|.|..|.||:..:.: |  :|..|
  Fly    31 VEKQQR-----KSRAIVSI-PNTIKLSMLNSGLLSFERIKLEARDENNSLSKTIPN-GPIDIRHF 88

Human   357 VSIPTPREKVAMEY---LQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTK 418
            :.:...|.|..:.|   .|:|:::.:.:       ..|.|:...:|                  |
  Fly    89 LKLCDLRRKFPVLYKLEFQTAAKVESNT-------CRHALKKNNLE------------------K 128

Human   419 NRYKTILPNPLSRVCL-RPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQ 482
            |:....:|...:||.| :...:.|  |.|:||:|:.... |..|:|.||||:..||..:|:||||
  Fly   129 NQNPKCIPYDYNRVVLEKVGGLQD--SDYVNASYVDSLL-KPNAYIVTQGPVEETVQAYWRMVWQ 190

Human   483 EDSPVIVMITKLKE-KNEKCVLYWPEKRGI---YGKVEVLVISVNECDNYTIRNLVLKQGSHTQH 543
            |:...|||:||..: ....|..|||....:   ||.:.:.::...:..|:.||...|.:.:..|.
  Fly   191 ENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQE 255

Human   544 VK------HYWYTSWPDHKTPDSAQPLLQLMLDV---------EEDRLASQGRGPVVVHCSAGIG 593
            |.      .:.||.|..|..|.| ..||:....|         :||.:    |||::||||.|.|
  Fly   256 VTDERLILQFHYTEWYSHSCPFS-NALLEFRRRVRLVVGNIIKDEDDM----RGPILVHCSDGGG 315

Human   594 RTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVH-----HALC 645
            |:|.:::.....:..:||...:....:.:||..|.|:|:..|||:|::     |.:|
  Fly   316 RSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIIC 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPRR	NP_002840.2	R-PTPc-R	417..642	CDD:350459	77/249 (31%)
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	78/268 (29%)
		Y_phosphatase	428..671	CDD:459674