Protein Alignment ACTA1 and Act87E

DIOPT Version :10

• Sequence 1: NP_001091.1
• Gene: ACTA1 / 58
• HGNCID: 129
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_477091.1
• Gene: Act87E / 48632
• FlyBaseID: FBgn0000046
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 352/377 - (93%)
• Similarity: 363/377 - (96%)
• Gaps: 1/377 - (0%)

Human     1 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 65
            ||| ||..|||.|||||:.||||||||||||||||||||||||||||||||||||||||||||||
  Fly     1 MCD-DEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 64

Human    66 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFN 130
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
  Fly    65 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN 129

Human   131 VPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 195
            .||||||||||||||||||||||||||||||:|.|||||||||||||:|||||||||||||||||
  Fly   130 APAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKIL 194

Human   196 TERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCP 260
            |||||||.|||||||||||||||||||||||.||||||:|:||||||||||||||||||||||||
  Fly   195 TERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCP 259

Human   261 ETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS 325
            |:||||||:||||.|||||.||||||||:|||||||||.||||||||||||||||||||||||||
  Fly   260 ESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPS 324

Human   326 TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377
            |:||||||||||||||||||||||||||||||||:||||||:||.|||||||
  Fly   325 TIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTA1	NP_001091.1	ASKHA_NBD_actin	8..372	CDD:466823	340/363 (94%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	112..125		12/12 (100%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	360..372		8/11 (73%)
Act87E	NP_477091.1	ASKHA_NBD_actin	7..371	CDD:466823	340/363 (94%)