Protein Alignment ACTA1 and Act88F

DIOPT Version :9

• Sequence 1: NP_001091.1
• Gene: ACTA1 / 58
• HGNCID: 129
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 349/377 - (92%)
• Similarity: 363/377 - (96%)
• Gaps: 1/377 - (0%)

Human     1 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 65
            ||| |:..|||.|||||:.||||||||||||||||||||||||||||||||||||||||||||||
  Fly     1 MCD-DDAGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 64

Human    66 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFN 130
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
  Fly    65 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN 129

Human   131 VPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 195
            .||||||||||||||||||||||||||||||:|.||||||:||||||:|||||||||||||||||
  Fly   130 SPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKIL 194

Human   196 TERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCP 260
            |||||||.|||||||||||||||||||||||.||||||:|:||||||||||||||||||||||||
  Fly   195 TERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCP 259

Human   261 ETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS 325
            |.||||||:||||.|||||.||||||||:|||||||||:|:||||||||||||||||||||||||
  Fly   260 EALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPS 324

Human   326 TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377
            |:||||||||||||||||||||||||||||||||:||||||:||.|||||||
  Fly   325 TIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTA1	NP_001091.1	PTZ00281	4..377	CDD:173506	344/372 (92%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	112..125		12/12 (100%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	360..372		8/11 (73%)
Act88F	NP_524367.1	PTZ00281	1..376	CDD:173506	347/375 (93%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54227
OrthoDB	1	1.010	-	-		D283838at33208
OrthoFinder	1	1.000	-	-		FOG0000057
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100127
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X104
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730