Protein Alignment ACTA1 and Act79B

DIOPT Version :10

• Sequence 1: NP_001091.1
• Gene: ACTA1 / 58
• HGNCID: 129
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_524210.1
• Gene: Act79B / 40444
• FlyBaseID: FBgn0000045
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 347/377 - (92%)
• Similarity: 361/377 - (95%)
• Gaps: 1/377 - (0%)

Human     1 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 65
            |||| |.:|||.|||||:.||||||||||||||||||||||||||||||||||.|||||||||||
  Fly     1 MCDE-EASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDEAQSKRG 64

Human    66 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFN 130
            ||:||||||||||||||||||:|||||||||||||||||.|||||||||||||||||||||||||
  Fly    65 ILSLKYPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN 129

Human   131 VPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 195
            .||||||||||||||||||||||||||||||:|.|||||||||||||:|||||||||||||||||
  Fly   130 SPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKIL 194

Human   196 TERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCP 260
            |||||||.|||||||||||||||||||||||.||||||:|:||||||||||||||||||||||.|
  Fly   195 TERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRTP 259

Human   261 ETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS 325
            |.||||||:||||.|||||.|.||||||:|||||||||||:||||||||||||||||||||||||
  Fly   260 EALFQPSFLGMESCGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPS 324

Human   326 TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377
            |:||||||||||||||||||||||||||||||||:||||||:||.|||||||
  Fly   325 TIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTA1	NP_001091.1	ASKHA_NBD_actin	8..372	CDD:466823	335/363 (92%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	112..125		12/12 (100%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	360..372		8/11 (73%)
Act79B	NP_524210.1	ASKHA_NBD_actin	7..371	CDD:466823	335/363 (92%)