Protein Alignment NKX3-2 and bap

DIOPT Version :9

• Sequence 1: NP_001180.1
• Gene: NKX3-2 / 579
• HGNCID: 951
• Length: 333
• Species: Homo sapiens
• Sequence 2: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 364
• Identity: 117/364 - (32%)
• Similarity: 153/364 - (42%)
• Gaps: 108/364 - (29%)

Human     1 MAVRGANTLTSFSIQAILNKKE-ERGGLAAPEGRPAP------GGTAASVAAAPAVCCWRLFGER 58
            ||....:..|.|||..||.:.. |...:::.:..|.|      .....|::.:|.:||      |
  Fly    13 MAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCC------R 71

Human    59 DAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAG--- 120
            |.|..      .|..|...:.    :|..|..:....|.:.:|.:...  .|.|.|.:..|.
  Fly    72 DLGLY------KLTQPKEIQP----SARQPSNYLQYYAAAMDNNNHHH--QATGTSNSSAADYMQ 124

Human   121 ------GSLSLGQPVCELAASKDLEEEAAGRS--DSEMSASVSGDRSPRTEDDGVGPRGAHVSAL 177
                  ||        .|||..|:....:..|  ||....|.|...||.:.|
  Fly   125 RKLAYFGS--------TLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHD------------- 168

Human   178 CSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAAS 242
                    |||.:              |||||||||||||||||||||..|||||||||:::|.|
  Fly   169 --------GSGLS--------------RKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKS 211

Human   243 LKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDD------------------ 289
            |:|||||||||||||||||||:|:.....|...|:|:|.|:||||:|
  Fly   212 LRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLD 276

Human   290 ---------QRQYLPGEVLRPPSLLPLQPSYYYPYYCLP 319
                     |.|...|.:..|...:|.  .|:||.:.:|
  Fly   277 PALINIYRHQLQLAYGGLPLPQMQMPF--PYFYPQHKVP 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKX3-2	NP_001180.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..113		7/47 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..212		17/75 (23%)
		Homeobox	209..262	CDD:278475	45/52 (87%)
bap	NP_732637.1	Homeobox	178..231	CDD:278475	45/52 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6687
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5408
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003099
OrthoInspector	1	1.000	-	-		oto90987
orthoMCL	1	0.900	-	-		OOG6_108109
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4480
SonicParanoid	1	1.000	-	-		X4759
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.750