DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Angptl4 and CG31832

DIOPT Version :9

Sequence 1:	NP_065606.2	Gene:	Angptl4 / 57875	MGIID:	1888999	Length:	410	Species:	Mus musculus
Sequence 2:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	223	Identity:	79/223 - (35%)
Similarity:	115/223 - (51%)	Gaps:	26/223 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse   195 LFQEGERH---------SGLFQIQPLGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKD 250
            ||:.|:..         :|:.|:......||.|....|:...|.||||||:|||:|||||.:|||
  Fly    14 LFEVGQSSPHTCPSGSPNGIHQLMLPEEEPFQVTQCKTTARDWIVIQRRLDGSVNFNQSWFSYKD 78

Mouse   251 GFGDPQGEFWLGLEKMHSITGNRGSQLAVQLQDWDGNAKLLQF-PIHLGGEDTAYSLQLT---EP 311
            |||||.|||::||:|::.:|..:..:|.:||:...|......| ...:..|...|.|:..   ..
  Fly    79 GFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSG 143

Mouse   312 TANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHSIPRQRQ 376
            ||.:....:::..     |||:|:|:| ....|||....|||||.:|..|:|||.||    |:.:
  Fly   144 TAGDSLRYHINKR-----FSTFDRDND-ESSKNCAAEHGGGWWFHSCLSSSLNGLYF----REGE 198

Mouse   377 E-RKKGIFWKTWKGRYYPLQATTLLIQP 403
            . ...||.|..||  :..|....::|:|
  Fly   199 TGMLNGIHWGRWK--FQSLTFVQIMIRP 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Angptl4	NP_065606.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..101
		Fib_alpha	<104..133	CDD:285864
		FReD	187..404	CDD:238040	79/223 (35%)
CG31832	NP_723894.2	FReD	28..225	CDD:238040	76/209 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810