DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZNF410 and CG31224

DIOPT Version :9

Sequence 1:	NP_001229853.1	Gene:	ZNF410 / 57862	HGNCID:	20144	Length:	516	Species:	Homo sapiens
Sequence 2:	NP_001287396.1	Gene:	CG31224 / 42237	FlyBaseID:	FBgn0051224	Length:	1784	Species:	Drosophila melanogaster

Alignment Length:	149	Identity:	49/149 - (32%)
Similarity:	72/149 - (48%)	Gaps:	10/149 - (6%)

- Green bases have known domain annotations that are detailed below.

Human   233 EKKLKCTVEGCDRTFVWPAHFKYHLKTH--RNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKP 295
            |.:..|.:  |.::|....:.|.|...|  |..:.|.|  |.|.|:|......|.|:..|...||
  Fly  1635 EPQYDCAI--CSKSFSTKWNLKIHSWVHANRTAKPFKC--EYCPKAFVRELDFKNHINAHKQIKP 1695

Human   296 FMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQV 360
            :.|...||  :|....|...|||.|.|.|.|.|:.  |.:||..:..|.:|..:|:||:|..|.:
  Fly  1696 YTCEYCGC--KFIRKYNYMRHRREHHGTKKFTCDQ--CDKSFHRHYYLIEHRRMHTGERPFTCTI 1756

Human   361 CGKTFSQSGSRNVHMRKHH 379
            |||:.:...:.|.|::.||
  Fly  1757 CGKSSTTKTNHNKHLKIHH 1775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZNF410	NP_001229853.1	zf-C2H2_8	268..351	CDD:292531	28/82 (34%)
		C2H2 Zn finger	271..290	CDD:275370	6/18 (33%)
		zf-H2C2_2	283..309	CDD:290200	9/25 (36%)
		C2H2 Zn finger	298..320	CDD:275368	8/21 (38%)
		zf-H2C2_2	312..338	CDD:290200	11/25 (44%)
		C2H2 Zn finger	328..350	CDD:275368	6/21 (29%)
		zf-H2C2_2	342..367	CDD:290200	10/24 (42%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
CG31224	NP_001287396.1	C2H2 Zn finger	1466..1486	CDD:275368
		C2H2 Zn finger	1494..1514	CDD:275368
		zf-H2C2_2	1506..1531	CDD:290200
		C2H2 Zn finger	1522..1542	CDD:275368
		PHA00733	1527..1623	CDD:177301
		C2H2 Zn finger	1554..1573	CDD:275370
		C2H2 Zn finger	1580..1599	CDD:275368
		C2H2 Zn finger	1613..1632	CDD:275368
		COG5048	<1637..1780	CDD:227381	48/147 (33%)
		C2H2 Zn finger	1640..1660	CDD:275368	5/21 (24%)
		C2H2 Zn finger	1670..1690	CDD:275368	7/21 (33%)
		C2H2 Zn finger	1698..1718	CDD:275368	8/21 (38%)
		zf-H2C2_2	1710..1735	CDD:290200	12/26 (46%)
		C2H2 Zn finger	1726..1746	CDD:275368	6/21 (29%)
		zf-H2C2_2	1738..1763	CDD:290200	10/24 (42%)
		C2H2 Zn finger	1754..1774	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910