Protein Alignment PTPRA and Ptp61F

DIOPT Version :10

• Sequence 1: NP_001372231.1
• Gene: PTPRA / 5786
• HGNCID: 9664
• Length: 813
• Species: Homo sapiens
• Sequence 2: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Alignment Length: 374
• Identity: 111/374 - (29%)
• Similarity: 186/374 - (49%)
• Gaps: 68/374 - (18%)

Human   236 KLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEE-----------NKEKNRYVNILPYD 289
            ::|.|...:....::.::|         |..||:..:||:           |:..|||.::.|||
  Fly    18 QIEAEYKDKGPQWHRFYKE---------ICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYD 73

Human   290 HSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLK 354
            |||:.|.  .|  ..|||||:.:...:.:.::|..|||..:||..||.|:|||.:..::|:..|.
  Fly    74 HSRIVLK--RG--SVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLM 134

Human   355 ERKECKCAQYWPDQ----GCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQ--RLITQ 413
            |:|:.||..|||::    ......:::::||.|.:   .|.:.| :::...:|:.:.|  |.:.|
  Fly   135 EKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRL---ETYQNF-VRRWFKLTDLETQQSREVMQ 195

Human   414 FHFTSWPDFGVPFTPIGMLKFLKKVK--ACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTE 476
            ||:|:|||||:|.:|...||||::|:  .|..:..|..|||||||:||:|||.::|..|.::...
  Fly   196 FHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKY 260

Human   477 RKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE-----H---YLYGDTELEVTSLETH-LQKI 532
            .:.:|...:..:|:.|..::||..|..|.|||::|     |   :|..:..|.....||| |.::
  Fly   261 GECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEGIKKLHDPTFLDAEEPLISNDTETHTLDEL 325

Human   533 YNKIP-----------------------GTSNNGLEEEFKKLTSIKIQN 558
            ...:|                       ....||.|...|:|:...:.|
  Fly   326 PPPLPPRVQSLNLPLAPNSGGILSLNMRAAQANGAESIGKELSKDALNN 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPRA	NP_001372231.1	R-PTPc-A-1	225..520	CDD:350469	99/310 (32%)
		R-PTPc-A-2	574..801	CDD:350471
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	84/235 (36%)