Protein Alignment HES4 and Hesr

DIOPT Version :10

• Sequence 1: NP_001135939.1
• Gene: HES4 / 57801
• HGNCID: 24149
• Length: 247
• Species: Homo sapiens
• Sequence 2: NP_525094.1
• Gene: Hesr / 32800
• FlyBaseID: FBgn0030899
• Length: 149
• Species: Drosophila melanogaster
• Alignment Length: 122
• Identity: 38/122 - (31%)
• Similarity: 64/122 - (52%)
• Gaps: 10/122 - (8%)

Human    65 KPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSAD 129
            ||:||::||:|||..|..:|.|:.:....:....:|::..|:||:.|.|| |.:...|....:|.
  Fly    26 KPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAVHHL-SKKNCPVATPTTAP 89

Human   130 PAVLGKYR-------AGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPS 179
            .:  |.|:       :||.||:.||::||......|:...::.|.||.|...:..|:
  Fly    90 TS--GVYQSPIDCYWSGFRECVLEVSQFLQHNGYQPSFEFAKELDHLVASTSKSKPN 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HES4	NP_001135939.1	bHLH-O_HES1_4	62..121	CDD:381465	20/55 (36%)
		Hairy_orange	135..174	CDD:462193	14/45 (31%)
Hesr	NP_525094.1	bHLH_SF	16..77	CDD:469605	19/51 (37%)
		Hairy_orange	101..>116	CDD:470640	6/14 (43%)