Protein Alignment TRIB3 and YPL150W

DIOPT Version :10

• Sequence 1: NP_001288130.1
• Gene: TRIB3 / 57761
• HGNCID: 16228
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_015175.1
• Gene: YPL150W / 855953
• SGDID: S000006071
• Length: 901
• Species: Saccharomyces cerevisiae
• Alignment Length: 272
• Identity: 75/272 - (27%)
• Similarity: 119/272 - (43%)
• Gaps: 40/272 - (14%)

Human    93 SRLGPY-VLLEPEEG--GRAYQALHCPTGTEYTCKVYPVQEALAVLEP-YARLPPHKHVARPTEV 153
            :.:|.| :|.:..||  |:.|.|||.||..:...|.....:...|.|. |.|.....::.:..||
Yeast    36 TEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYEV 100

Human   154 LAGTQLLYAFFTRTHG-DMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVF 217
            :.....::.......| :::..:.|..||...|...||.|::.|:.:.|....|.||||| ..:.
Yeast   101 IVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKL-ENIL 164

Human   218 ADRE-----------RKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADV 271
            .|:.           |:.:....||..|..|             .|:.||:: .|.:|.|...|:
Yeast   165 LDKNGNAKLTDFGFTRECMTKTTLETVCGTT-------------VYMAPELI-ERRTYDGFKIDI 215

Human   272 WSLGVALFTMLAGHYPFQDSEPVLLFGKI-----RRGAYALPAGLSAPARCLVRCLLRREPAERL 331
            |||||.|:|::.|:.||.|.:......||     :..|..:|    ..||.|:..||.:.|.||.
Yeast   216 WSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIP----DDARDLISRLLAKNPGERP 276

Human   332 TATGILLHPWLR 343
            :.:.:|.||:|:
Yeast   277 SLSQVLRHPFLQ 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB3	NP_001288130.1	PK_TRB3	101..342	CDD:270926	71/260 (27%)
YPL150W	NP_015175.1	STKc_AMPK-like	40..286	CDD:270905	72/264 (27%)