Protein Alignment TRIB3 and SNF1

DIOPT Version :10

• Sequence 1: NP_001288130.1
• Gene: TRIB3 / 57761
• HGNCID: 16228
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_010765.3
• Gene: SNF1 / 852088
• SGDID: S000002885
• Length: 633
• Species: Saccharomyces cerevisiae
• Alignment Length: 316
• Identity: 88/316 - (27%)
• Similarity: 141/316 - (44%)
• Gaps: 37/316 - (11%)

Human    78 SPPTAPDRATAVATASRLGPYVLLEP-EEG--GRAYQALHCPTGTEYTCKVYPVQEALAVLE--- 136
            |..|..:..:::|..:.:|.|.:::. .||  |:...|.|..||.:...|:.. ::.||..:
Yeast    35 SNSTLNNPKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIIN-KKVLAKSDMQG 98

Human   137 ------PYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMAT 195
                  .|.||..|.|:.:..:|:.....:.........::...:..|.::.|.||...|:|:.:
Yeast    99 RIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIIS 163

Human   196 ALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHAC--PAYVGPEIL 258
            |:.:||:|.:|.||||....:..:....|:....|  |.::|   |..:.|.:|  |.|..||::
Yeast   164 AVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGL--SNIMT---DGNFLKTSCGSPNYAAPEVI 223

Human   259 SSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLL 323
            |.:. |:|...||||.||.|:.||....||.|....:||..|..|.|.||..||..|..|::.:|
Yeast   224 SGKL-YAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRML 287

Human   324 RREPAERLTATGILLHPWLRQD-PMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGD 378
            ...|..|::...|:...|.:.| |..|.|            ||   |....|||.:
Yeast   288 IVNPLNRISIHEIMQDDWFKVDLPEYLLP------------PD---LKPHPEEENE 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB3	NP_001288130.1	PK_TRB3	101..342	CDD:270926	72/254 (28%)
SNF1	NP_010765.3	STKc_AMPK_alpha	52..306	CDD:270981	74/260 (28%)
		UBA_2	344..389	CDD:430091
		AdenylateSensor	504..626	CDD:406881