Protein Alignment TRIB3 and trbl

DIOPT Version :9

• Sequence 1: NP_001288130.1
• Gene: TRIB3 / 57761
• HGNCID: 16228
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_524672.1
• Gene: trbl / 43999
• FlyBaseID: FBgn0028978
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 104/288 - (36%)
• Similarity: 145/288 - (50%)
• Gaps: 36/288 - (12%)

Human   117 TGTEYTCKVYPVQEAL-AVLEPYARLPPHKHVARPTEVLA----------------GTQLLYA-- 162
            ||.::.|::  |.|.| .|...|.:|..|....|.:.:..                .|.:|.|
  Fly   147 TGEQFLCRI--VNEPLHKVQRAYFQLQQHDEELRRSTIYGHPLIRPVHDIIPLTKDRTYILIAPV 209

Human   163 --------FFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFAD 219
                    ..|..:.::|:.:|...|:.|.||..:|.|:...:..||::|::||||||.||.|.|
  Fly   210 PQERDSTGGVTGVYENLHTYIRHAKRLCETEARAIFHQICQTVQVCHRNGIILRDLKLKRFYFID 274

Human   220 RERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAG 284
            ..|.||..|:||.|.:|.|.||:|.||..||.|..||:|..:.:|.||.||:|||||.|:|||.|
  Fly   275 EARTKLQYESLEGSMILDGEDDTLSDKIGCPLYTAPELLCPQQTYKGKPADMWSLGVILYTMLVG 339

Human   285 HYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPL 349
            .|||.:.....|...||.|...:|..||...|.|:..|||::..||:||:.|.|.||||:.
  Fly   340 QYPFYEKANCNLITVIRHGNVQIPLTLSKSVRWLLLSLLRKDYTERMTASHIFLTPWLREQ---- 400

Human   350 APTRSHLWEAAQVVPDGLGLDEAREEEG 377
            .|...:|....:|..|   ..:|.|:||
  Fly   401 RPFHMYLPVDVEVAED---WSDAEEDEG 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB3	NP_001288130.1	PK_TRB3	101..342	CDD:270926	93/251 (37%)
		S_TKc	107..342	CDD:214567	93/251 (37%)
trbl	NP_524672.1	PKc_like	131..397	CDD:328722	93/251 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159489
Domainoid	1	1.000	181	1.000	Domainoid score	I3485
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3953
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362510at2759
OrthoFinder	1	1.000	-	-		FOG0001790
OrthoInspector	1	1.000	-	-		otm40776
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22961
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1487
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.960