Protein Alignment TRIB3 and trib3

DIOPT Version :10

• Sequence 1: NP_001288130.1
• Gene: TRIB3 / 57761
• HGNCID: 16228
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_998034.1
• Gene: trib3 / 405805
• ZFINID: ZDB-GENE-040426-2609
• Length: 348
• Species: Danio rerio
• Alignment Length: 336
• Identity: 175/336 - (52%)
• Similarity: 227/336 - (67%)
• Gaps: 5/336 - (1%)

Human    33 LAAPAGSLSRKKRLELDD--NLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRL 95
            |:.|...| |.||::.:|  :.||.:..::|....|.|.|.|||.||| .:.....:.....||:
Zfish     5 LSTPTPPL-RLKRVDFEDSHSNDTFKCKRRRLSQPPSPGLAPCLRPLS-QSLEQPGSEKHHVSRI 67

Human    96 GPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLL 160
            |||:|||..|..:.::|:|..|..||||||:.:::....:.||.||.||.::.:.:||:.|...:
Zfish    68 GPYILLEATEVAQTFRAVHQVTEQEYTCKVFSMKKYHEFIAPYTRLLPHSNICKISEVVLGENNV 132

Human   161 YAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKL 225
            |.||.|.:|||||.||:..|:.|.||..||.|||:|:||||::|::||||||.:|||.|::|.||
Zfish   133 YIFFERNYGDMHSYVRTCKRLQEDEAVRLFTQMASAVAHCHENGVILRDLKLRKFVFTDQQRTKL 197

Human   226 VLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQD 290
            ||:||||||:|.|.||||.|||.||||||||||:||.||||||||:|||||.|:|||.|.|||||
Zfish   198 VLQNLEDSCLLNGNDDSLTDKHGCPAYVGPEILNSRHSYSGKAADIWSLGVVLYTMLVGRYPFQD 262

Human   291 SEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLR-QDPMPLAPTRS 354
            .||..||.||||||:.:|..||..|:.||.|:||:.|:|||.|..|||||||. .:...|:...|
Zfish   263 VEPTALFSKIRRGAFTVPETLSPRAKSLVYCMLRKCPSERLEAGDILLHPWLHCNNSTSLSQHSS 327

Human   355 HLWEAAQVVPD 365
            ......|||||
Zfish   328 SRHSTDQVVPD 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB3	NP_001288130.1	PK_TRB3	101..342	CDD:270926	141/240 (59%)
trib3	NP_998034.1	PK_TRB3	73..314	CDD:270926	141/240 (59%)