Protein Alignment TRIB3 and ppk27

DIOPT Version :10

• Sequence 1: NP_001288130.1
• Gene: TRIB3 / 57761
• HGNCID: 16228
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_595405.1
• Gene: ppk27 / 2540313
• PomBaseID: SPBC337.04
• Length: 413
• Species: Schizosaccharomyces pombe
• Alignment Length: 257
• Identity: 58/257 - (22%)
• Similarity: 88/257 - (34%)
• Gaps: 98/257 - (38%)

Human   144 HKHVA------RPTEVLAGTQLLYAFFTRTH-------------------------GDMHSLVRS 177
            |.|::      :...|....|.::|..|.:|                         ||::...:.
pombe   134 HTHLSSKSQNEKKARVKVFRQEIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKK 198

Human   178 RHRIPEPE-AAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDD 241
            .|.....| ...:|.::...:|:.|...|:.||||               |||:    :||.|.:
pombe   199 HHSDFSLEFVGRIFSELVHTVAYLHSKCLIHRDLK---------------LENI----LLTQPYN 244

Human   242 SL-----WDKH-------------------------ACPA--YVGPEILSSRASYSGKAADVWSL 274
            .:     |..:                         :|.:  |..||:....| :.|..||.|||
pombe   245 VIKTIDNWKNYPNALIQISDFELSIFVDSKNHLVQSSCGSQEYAPPEVYMGIA-HDGFRADAWSL 308

Human   275 GVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRC----LLRREPAERLT 332
            |:.||.:|.|..|| ||.|.|....:|...|         .:.||||    .|.:.|.:|.|
pombe   309 GIVLFALLEGRLPF-DSYPTLDPENVRIKRY---------VQRLVRCDYTWHLCKSPFKRST 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB3	NP_001288130.1	PK_TRB3	101..342	CDD:270926	58/257 (23%)
ppk27	NP_595405.1	Protein Kinases, catalytic domain	144..396	CDD:473864	56/247 (23%)