Protein Alignment PTPN4 and Ptpn4

DIOPT Version :10

• Sequence 1: NP_002821.1
• Gene: PTPN4 / 5775
• HGNCID: 9656
• Length: 926
• Species: Homo sapiens
• Sequence 2: NP_064317.2
• Gene: Ptpn4 / 19258
• MGIID: 1099792
• Length: 926
• Species: Mus musculus
• Alignment Length: 926
• Identity: 877/926 - (94%)
• Similarity: 908/926 - (98%)
• Gaps: 0/926 - (0%)

Human     1 MTSRFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLT 65
            ||:||||||||||||||||||||||||||||||||||||||||:||||||||||||:||||||||
Mouse     1 MTARFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLT 65

Human    66 EQDYFGLQLADDSTDNPRWLDPNKPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQI 130
            |:||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||
Mouse    66 ERDYFGLQLADDSTDNPRWLDPNKPIRKQLKRGSPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQI 130

Human   131 KQDILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQH 195
            |||||||||.||.||||||||||||||||||:|||||:|||||||||||||||||||||||||||
Mouse   131 KQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQH 195

Human   196 IGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTFPWLKIVK 260
            :|||||||||||||.||||||||||||||||||||||:||||||||||||||||||||.||||||
Mouse   196 VGLSPAEAEFNYLNAARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFLWLKIVK 260

Human   261 ISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAHYF 325
            |||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||
Mouse   261 ISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAHYF 325

Human   326 TLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSISDDRLETQSLPS 390
            ||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||
Mouse   326 TLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPS 390

Human   391 RSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMVHTSPSEVFVNQRSPSSTQANSIVLESSPSQE 455
            ||||||||||||:||||.||:|||||||||||:||.||||.||:|||||||||||||||||||||
Mouse   391 RSPPGTPNHRNSSFTQEATRVRPSSVGHLVDHVVHMSPSEDFVSQRSPSSTQANSIVLESSPSQE 455

Human   456 TPGDGKPPALPPKQSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIPHDNLVLIRM 520
            ||.||:||||||||||||||||||:|:|||||.:|.||:||:||||||.||||||||||||||:|
Mouse   456 TPEDGQPPALPPKQSKKNSWNQIHFSNSQQDLVTHTNESFDVPSSPEKSTPNGGIPHDNLVLIKM 520

Human   521 KPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLF 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 KPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLF 585

Human   586 IKASCERHSGELMLLVRPNAVYDVVEEKLENEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGL 650
            ||||||:|||||:|||||||||||||||||:||||||||||||||||||||||||||||||||||
Mouse   586 IKASCEKHSGELVLLVRPNAVYDVVEEKLESEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGL 650

Human   651 ITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNEDYINANYINMEIP 715
            ||||||.|||||||||||||||||||||||||||||||||||||||:||||||||||||||||||
Mouse   651 ITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKGNEDYINANYINMEIP 715

Human   716 SSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPTGSSSYGCYQ 780
            |||||||||||||||||||.|||||||||||||||||||||||||||||||||||:.||||||||
Mouse   716 SSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPSESSSYGCYQ 780

Human   781 VTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKE 845
            |||||||||.||||||||||||||||||.||||||.||||||||||||||||||||||::|||||
Mouse   781 VTCHSEEGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRDQRAGKE 845

Human   846 EPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILK 910
            ||::|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   846 EPIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILK 910

Human   911 VYEEGFVKPLTTSTNK 926
            |||||||||||||:||
Mouse   911 VYEEGFVKPLTTSSNK 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPN4	NP_002821.1	B41	30..222	CDD:214604	181/191 (95%)
		FERM_C_PTPN4_PTPN3_like	216..310	CDD:270010	90/93 (97%)
		FA	324..365	CDD:462582	40/40 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..412		29/31 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	430..475		40/44 (91%)
		PDZ_PTPN3-4-like	513..602	CDD:467190	85/88 (97%)
		PTP_DSP_cys	641..914	CDD:475123	260/272 (96%)
Ptpn4	NP_064317.2	B41	30..222	CDD:214604	181/191 (95%)
		FERM_C_PTPN4_PTPN3_like	216..310	CDD:270010	90/93 (97%)
		FA	324..365	CDD:462582	40/40 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..412		30/32 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..474		40/44 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	492..511		15/18 (83%)
		PDZ_PTPN3-4-like	513..602	CDD:467190	85/88 (97%)
		PTP_DSP_cys	641..914	CDD:475123	260/272 (96%)