DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ANKRD36B and Potegl

DIOPT Version :9

Sequence 1:NP_001380868.1 Gene:ANKRD36B / 57730 HGNCID:29333 Length:1353 Species:Homo sapiens
Sequence 2:NP_081911.1 Gene:Potegl / 70981 MGIID:1918231 Length:382 Species:Mus musculus


Alignment Length:306 Identity:103/306 - (33%)
Similarity:167/306 - (54%) Gaps:11/306 - (3%)


- Green bases have known domain annotations that are detailed below.


Human    24 IHRAVLRGNLEKLK-YLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR 87
            :|.|...|:|..:: |..|..|:.|.|||:.|.|:|.||..|..|:|..|..|.||:|:||..:.
Mouse    67 LHMAACAGDLPFVRLYFTLGKYEVNHRDRENRNAMHFACFYGHLELVIYLWRRGCEINVCDNHNI 131

Human    88 TPLIKAVQLRQEACATLLLQNGADPNITDVFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKNE 152
            |||:||||..::.....||::.|:.:|.|..|.||||||||:.:.:...:||.:|.:|||.:|:.
Mouse   132 TPLMKAVQSWEDKIVCFLLEHHANLHIKDSMGNTALHYAVYSGNLATAARLLQYGADIEERTKDN 196

Human   153 YQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRDVY 217
            ..|||||:...::||.:||::.:|:|:|:|...|::|:.||......:|.|:||..:|:..:|::
Mouse   197 LTPLLLALRENRLKMAQFLVRMEASVHAVDSQRRNSLMYAVRCDSPVMVNLILQQGVDINLKDLF 261

Human   218 GKLAEDYASEAENRVIFDLIYEYKRKRYEDLPINSNPVSPQKQRAEKATSDDKDSVSNIATEIKE 282
            |..|..||.|.:..|...|:...||.|......||:.....|..||..:....:.|..:......
Mouse   262 GWTALRYAIEGDRDVRTMLLELRKRNRAFQSSENSSIRLINKADAEVTSPTANEKVIEMQDPFTT 326

Human   283 GPISGTVSSQKQPAEK-----ATSDE---KDSVSNIATEIKEGQQS 320
            ...|...:..::|||.     :..:|   |::::|:  :...||:|
Mouse   327 NEASVEKTQTRRPAESELEVFSLEEEISYKETINNL--QQNPGQRS 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ANKRD36BNP_001380868.1 ANKYR 17..209 CDD:223738 75/185 (41%)
ANK 1 19..48 7/24 (29%)
Ank_2 24..116 CDD:403870 37/92 (40%)
ANK repeat 24..50 CDD:293786 8/26 (31%)
ANK 2 52..81 12/28 (43%)
ANK repeat 54..83 CDD:293786 13/28 (46%)
ANK repeat 85..116 CDD:293786 11/30 (37%)
ANK 3 85..114 10/28 (36%)
ANK 4 118..147 13/28 (46%)
ANK repeat 118..142 CDD:293786 11/23 (48%)
ANK repeat 151..182 CDD:293786 12/30 (40%)
ANK 5 151..180 11/28 (39%)
ANK repeat 184..215 CDD:293786 9/30 (30%)
ANK 6 184..213 9/28 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..307 12/65 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 349..607
CCDC158 712..>1342 CDD:318193
CCDC144C 949..1240 CDD:405585
PoteglNP_081911.1 Ank_4 67..116 CDD:290365 19/48 (40%)
ANK 91..216 CDD:238125 55/124 (44%)
ANK repeat 96..127 CDD:293786 13/30 (43%)
Ank_2 102..192 CDD:289560 39/89 (44%)
ANK repeat 132..160 CDD:293786 11/27 (41%)
ANK 158..281 CDD:238125 47/122 (39%)
ANK repeat 162..193 CDD:293786 15/30 (50%)
Ank_2 167..259 CDD:289560 35/91 (38%)
ANK repeat 195..226 CDD:293786 12/30 (40%)
ANK repeat 228..259 CDD:293786 9/30 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BCY7
HGNC 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D24863at7742
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

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