Protein Alignment PTPN1 and pyp3

DIOPT Version :10

• Sequence 1: NP_002818.1
• Gene: PTPN1 / 5770
• HGNCID: 9642
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_594934.1
• Gene: pyp3 / 2541443
• PomBaseID: SPAC11E3.09
• Length: 303
• Species: Schizosaccharomyces pombe
• Alignment Length: 273
• Identity: 99/273 - (36%)
• Similarity: 152/273 - (55%)
• Gaps: 36/273 - (13%)

Human    33 RVAKLPKNK-NRNRYRDVSPFDHSRIKLH---QEDNDYINASLIKMEEAQRSYILTQGPLPNTCG 93
            |:.||.|.. .||||.::.|::::|::|.   :|..||||||::|:... :::|.||||..|:..
pombe    41 RLPKLSKKALARNRYSNIVPYENTRVRLDPMWKEACDYINASIVKIPSG-KTFIATQGPTSNSID 104

Human    94 HFWEMVWEQ--KSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNL-KLTLISEDIKSYYT- 154
            .||:|||:.  ||..:|||.::.|:..|||..|||.:     :||..|: .|::|   :...||
pombe   105 VFWKMVWQSVPKSGIIVMLTKLRERHRLKCDIYWPVE-----LFETLNIGDLSVI---LVKVYTL 161

Human   155 -------VRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSP--EHGP 210
                   ||:.||.....:  ::||||:|..|||||.|.: .|.|: |.:..:|.|.||  |..|
pombe   162 TSLNEVQVREFELNKDGVK--KKILHFYYNGWPDFGAPHT-FSLLS-LTRYIKSLSYSPDFETAP 222

Human   211 VVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVD---IKKVLLEMRKFRMGLIQTADQLRFSYL 272
            ::||||||.||:|||......|...|.....|..:   |..::..:|..||..:|:.|||.|.|.
pombe   223 IIVHCSAGCGRTGTFMALFEILSQTDDSTSTSKFEVDNIANIVSSLRSQRMQSVQSVDQLVFLYT 287

Human   273 A---VIEGAKFIM 282
            .   :::|.:|::
pombe   288 VSQELLQGKEFLL 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPN1	NP_002818.1	PTPc-N1	16..292	CDD:350456	99/273 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..359
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..398
pyp3	NP_594934.1	PTPc	29..288	CDD:214550	97/259 (37%)