Protein Alignment PTPN1 and Ptpn1

DIOPT Version :10

• Sequence 1: NP_002818.1
• Gene: PTPN1 / 5770
• HGNCID: 9642
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_036769.1
• Gene: Ptpn1 / 24697
• RGDID: 61965
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 433
• Identity: 368/433 - (84%)
• Similarity: 397/433 - (91%)
• Gaps: 2/433 - (0%)

Human     1 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDND 65
            ||||||||||||:|:||||||||||||||||||:|||||||||||||||||||||||||||||||
  Rat     1 MEMEKEFEQIDKAGNWAAIYQDIRHEASDFPCRIAKLPKNKNRNRYRDVSPFDHSRIKLHQEDND 65

Human    66 YINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEE 130
            |||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||
  Rat    66 YINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQKEE 130

Human   131 KEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFL 195
            |||:|:||||||||||||:||||||||||||||.|||.|||||||||||||||||||||||||||
  Rat   131 KEMVFDDTNLKLTLISEDVKSYYTVRQLELENLATQEAREILHFHYTTWPDFGVPESPASFLNFL 195

Human   196 FKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGL 260
            |||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||:|||||
  Rat   196 FKVRESGSLSPEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGL 260

Human   261 IQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCR 325
            |||||||||||||||||||||||||||||||||||||||||||||:|||||||||.||||||||:
  Rat   261 IQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHVPPPPRPPKRTLEPHNGKCK 325

Human   326 EFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKG 390
            |.|.|||||.||:.||:|...:||..:| :.|.:.:.|||||||||.|:|||.|:.|||:.|.:.
  Rat   326 ELFSNHQWVSEESCEDEDILAREESRAP-SIAVHSMSSMSQDTEVRKRMVGGGLQSAQASVPTEE 389

Human   391 EPSLPEKDED-HALSYWKPFLVNMCVATVLTAGAYLCYRFLFN 432
            |.|..|:::. |...:|||||||:|:||.|..|||||||..|:
  Rat   390 ELSPTEEEQKAHRPVHWKPFLVNVCMATALATGAYLCYRVCFH 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPN1	NP_002818.1	PTPc-N1	16..292	CDD:350456	266/275 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..359		7/20 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..398		8/19 (42%)
Ptpn1	NP_036769.1	PTPc-N1	16..292	CDD:350456	266/275 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..322		22/24 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..402		23/52 (44%)