Protein Alignment PTPN1 and Ptpn1

DIOPT Version :10

• Sequence 1: NP_002818.1
• Gene: PTPN1 / 5770
• HGNCID: 9642
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_035331.3
• Gene: Ptpn1 / 19246
• MGIID: 97805
• Length: 432
• Species: Mus musculus
• Alignment Length: 433
• Identity: 361/433 - (83%)
• Similarity: 394/433 - (90%)
• Gaps: 2/433 - (0%)

Human     1 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDND 65
            ||||||||:|||:|:|||||||||||||||||:||||||||||||||||||||||||||||||||
Mouse     1 MEMEKEFEEIDKAGNWAAIYQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDND 65

Human    66 YINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEE 130
            |||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||:||
Mouse    66 YINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQQEE 130

Human   131 KEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFL 195
            |||:|:||.|||||||||:||||||||||||||||:|||||||||||||||||||||||||||||
Mouse   131 KEMVFDDTGLKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWPDFGVPESPASFLNFL 195

Human   196 FKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGL 260
            ||||||||||.||||:|||||||||||||||||||||||||||||||||||||||||||:|||||
Mouse   196 FKVRESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGL 260

Human   261 IQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCR 325
            |||||||||||||||||||||||||||||||||||.|||:.||||:|||||||||.||||||||:
Mouse   261 IQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSREDLDLPPEHVPPPPRPPKRTLEPHNGKCK 325

Human   326 EFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKG 390
            |.|.:||||.|||..|:|...:|| |...::|.:.:.|||.|||||.|:|||.|:.|||:.|.:.
Mouse   326 ELFSSHQWVSEETCGDEDSLAREE-GRAQSSAMHSVSSMSPDTEVRRRMVGGGLQSAQASVPTEE 389

Human   391 E-PSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFN 432
            | .|..|:.:.|..|:|||||||:|:||:|..|||||||..|:
Mouse   390 ELSSTEEEHKAHWPSHWKPFLVNVCMATLLATGAYLCYRVCFH 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPN1	NP_002818.1	PTPc-N1	16..292	CDD:350456	264/275 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..359		7/20 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..398		8/20 (40%)
Ptpn1	NP_035331.3	PTPc-N1	16..292	CDD:350456	264/275 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..322		20/24 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..399		29/64 (45%)