Protein Alignment PTPN1 and ZK484.7

DIOPT Version :10

• Sequence 1: NP_002818.1
• Gene: PTPN1 / 5770
• HGNCID: 9642
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_491758.1
• Gene: ZK484.7 / 191327
• WormBaseID: WBGene00022753
• Length: 344
• Species: Caenorhabditis elegans
• Alignment Length: 265
• Identity: 80/265 - (30%)
• Similarity: 132/265 - (49%)
• Gaps: 32/265 - (12%)

Human    28 SDF-PCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQE-DNDYINASLIKMEEAQRSYILTQGPLPN 90
            :|| ..:..|..:...:|||:||...||:|:|||.. .:|||:|:.:......|.:|.||.||..
 Worm    66 NDFEKMKAFKEAQEHGKNRYKDVGCLDHNRVKLHPPWPHDYIHANFVSTPSNPRRFICTQAPLDK 130

Human    91 TCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTV 155
            :|..||.|..::|...:.||..:||||:.||..|:..|::..:.||:...|:      |..:.:.
 Worm   131 SCADFWYMCLQEKVDSIFMLCNIMEKGAKKCCDYFACKDKPVLEFEEKGHKI------IVKFEST 189

Human   156 RQLELENLTTQETRE--------------ILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSP 206
            .:::.|..|..:..|              :..:|:..|||.|||.:..:.:..|.|.|      |
 Worm   190 GKMKFEKNTDAKITETVFTVEGPGGLAQKVTQYHWIDWPDRGVPTADMAIVELLAKTR------P 248

Human   207 EHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSV-DIKKVLLEMRKFRMGLIQTADQLRFS 270
            ..||.||||||||||:|:..:.:   .::|:......: :..|:|.::|:.|...|||..|..|.
 Worm   249 SKGPTVVHCSAGIGRTGSVVMIE---YILDQLLGGQQIEETDKILQKIREQRNNSIQTDQQYLFV 310

Human   271 YLAVI 275
            :..::
 Worm   311 HQVIL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPN1	NP_002818.1	PTPc-N1	16..292	CDD:350456	80/265 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..359
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..398
ZK484.7	NP_491758.1	Y_phosphatase	80..316	CDD:459674	77/251 (31%)