Protein Alignment DDX55 and CG9630

DIOPT Version :10

• Sequence 1: XP_016875199.1
• Gene: DDX55 / 57696
• HGNCID: 20085
• Length: 618
• Species: Homo sapiens
• Sequence 2: NP_649777.1
• Gene: CG9630 / 40974
• FlyBaseID: FBgn0037561
• Length: 613
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 287/627 - (45%)
• Similarity: 411/627 - (65%)
• Gaps: 65/627 - (10%)

Human     9 WESL-PVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILL 72
            |.|| ..||...||..::..||..|||||:|.|||.:..|||:|||||||||||||::|:||||.
  Fly     6 WSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQ 70

Human    73 RREEKLK--KSQVGAIIITPTRELAIQIDEVLSHFTKH--FPEFSQILWIGGRNPGEDVERFKQQ 133
            ||.::..  ..::||::|:||||||.||.|||:.|.:|  ....:|.|.:||.:..||:...:::
  Fly    71 RRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGNSIEEDIATLRRE 135

Human   134 GGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRT 198
            ...|:|.|||||||:|:||.:.|:||:.|:||:.|||||||||||:||:.|:|.||.:||:||||
  Fly   136 TPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRT 200

Human   199 GLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFLR 263
            ||||||||.||.:|:||||||||.||||||     ::..||:||:|:|.:.:.:.||..|:.||.
  Fly   201 GLFSATQTTEVTDLIRAGLRNPVLVSVKEK-----ASVNTPARLQNFYRIVEPELKFVALLEFLS 260

Human   264 NHKQ--EKHLVFFRYSSGLCGRGIRDSARMCSTCACVEYYGKALEVLVKGVKIMCIHGKMKYKRN 326
            :...  .|.:|||                  .|||||||:.:||..|:....::.||||||.||.
  Fly   261 SPATVIGKVMVFF------------------PTCACVEYWAEALPPLLPKRTVLGIHGKMKNKRA 307

Human   327 KIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLL 391
            .:..:||.....:|:||||:|||:|:||:.||:|:||||.||:||||.|||||.|:.|:||||||
  Fly   308 NVVEKFRNTPQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLL 372

Human   392 PMEESYINFLAINQKCPLQEM---------KPQRNTADLLPKLKSMALADRAVFEKGMKAFVSYV 447
            |.|::|::||.||||..|.::         :.::....:|.:|..:..||:.|::|||:||||:|
  Fly   373 PSEDAYVHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHV 437

Human   448 QAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQFPDFV--PVDVNTDTIPFKDKIRE 510
            :||.||||:.|.||||||...:|..:.||::|:||||:..|...:|  ..:|:...:.:|:..:|
  Fly   438 RAYTKHECSAILRLKDLDLGKMATAYGLLQLPRMPELKNYQGGGYVAPAFEVDLSKLTYKNAQKE 502

Human   511 KQRQKLLE-----------QQRREKTENEGRRKFIKNKAWSK---QKAKKEKKK-------KMNE 554
            :.|||.:|           :|.:::.|:..:.|..|..|.||   :||||::||       :..:
  Fly   503 QVRQKKMETYEQTGSWPGQKQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEAEASRSGK 567

Human   555 KRKREEGSDIEDEDMEELLNDTRLLKKLKKGKITEEEFEKGL 596
            .:||::.|   .||::||.:|.||.|:|||.||:||:|:|.:
  Fly   568 GKKRQQFS---QEDLDELASDIRLFKRLKKNKISEEDFDKAM 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX55	XP_016875199.1	SrmB	16..438	CDD:440279	212/436 (49%)
		DEADc_DDX55	20..224	CDD:350718	118/207 (57%)
		DUF4217	423..480	CDD:464056	28/56 (50%)
CG9630	NP_649777.1	DEADc_DDX55	18..226	CDD:350718	118/207 (57%)
		SF2_C_DEAD	239..371	CDD:350174	66/149 (44%)
		DUF4217	414..470	CDD:464056	28/55 (51%)