Protein Alignment DDX55 and pths

DIOPT Version :10

• Sequence 1: XP_016875199.1
• Gene: DDX55 / 57696
• HGNCID: 20085
• Length: 618
• Species: Homo sapiens
• Sequence 2: NP_610090.1
• Gene: pths / 35379
• FlyBaseID: FBgn0032919
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 173/557 - (31%)
• Similarity: 258/557 - (46%)
• Gaps: 129/557 - (23%)

Human     8 SWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILL 72
            :|:.|  .|:..:..|..||.:...:.:|...||:.::.|||...|.||||||.||.:|||..||
  Fly    62 TWKDL--GLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHALL 124

Human    73 RREEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQI---------LWIGGRN-PGEDV 127
            ...::     ..|:::|||||||.||.|          :|..:         :.:||.: ..:.:
  Fly   125 ENPQR-----YFALVLTPTRELAFQIGE----------QFEALGSGIGIKCCVVVGGMDMVAQGL 174

Human   128 ERFKQQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFL 192
            :..|:.  :||:||||||.|.. ...:|.:|    :::..||:|||||:|:|.||..::.||:.|
  Fly   175 QLAKKP--HIIIATPGRLVDHL-ENMKGFNL----KAIKYLVMDEADRILNMDFEVELDKILKVL 232

Human   193 PKQRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQ 257
            |::|||.|||||.|::|:.|.||.|::||:|.|..|       .:|..:|:..|:......|...
  Fly   233 PRERRTFLFSATMTKKVKKLQRASLKDPVKVEVSNK-------YQTVEQLQQSYLFIPVKYKDVY 290

Human   258 LVHFLRNHKQEKHLVFFRYSSGLCGRGIRDSARMCSTCACVEYYGKALEVLVKGVKIMCIHGKM- 321
            |||.|........::|                  ||||.  .....||.:...|:..:.:||:|
  Fly   291 LVHILNELAGNSFMIF------------------CSTCN--NTVKTALMLRALGLAAIPLHGQMS 335

Human   322 KYKRNKIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSA 386
            :.||.....:|:.....||:.|||.:||:|||.|:.|:.:|.|:::..::||.|||||.|..|.|
  Fly   336 QNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKA 400

Human   387 LVFLLPME-ESY--INFLAINQ----KCPLQEMKPQRNTADLLPKLKSMALADRAVFEKGMKAFV 444
            :..:...: |.|  |..|...|    ||...|:               |||.:|          |
  Fly   401 ITLVSQYDIELYQRIEHLLGKQLTLYKCEEDEV---------------MALQER----------V 440

Human   445 SYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQFPDFVPVDVNTDTIPFKDKIR 509
            :..|..||.|      ||||:.   .||         ...||.        |.:.|:..|..
  Fly   441 AEAQRTAKLE------LKDLED---TRG---------GHKRGG--------DTHDDSENFTG--- 476

Human   510 EKQRQKLLEQQRREKTENEGRRKFIKNKAWSKQKAKK 546
            .::|.|.:     ..|...||:.|.| |.|||.|.|:
  Fly   477 ARKRMKPM-----GGTGGGGRKSFGK-KNWSKGKQKR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX55	XP_016875199.1	SrmB	16..438	CDD:440279	142/439 (32%)
		DEADc_DDX55	20..224	CDD:350718	80/213 (38%)
		DUF4217	423..480	CDD:464056	15/56 (27%)
pths	NP_610090.1	SrmB	62..480	CDD:440279	160/522 (31%)