Protein Alignment DDX55 and CG32344

DIOPT Version :10

• Sequence 1: XP_016875199.1
• Gene: DDX55 / 57696
• HGNCID: 20085
• Length: 618
• Species: Homo sapiens
• Sequence 2: NP_612028.4
• Gene: CG32344 / 326208
• FlyBaseID: FBgn0052344
• Length: 827
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 175/696 - (25%)
• Similarity: 293/696 - (42%)
• Gaps: 159/696 - (22%)

Human     7 GSWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEIL 71
            |.::|:.:..  :::..:.:.|:...||:|..||||.:..:||.|.|.||||||..|:||:.|.|
  Fly    39 GGFQSMGLGF--ELIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKL 101

Human    72 LRREEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQGGN 136
            .|||   ......|:|::||||||:|..:.:....: |.|...||.:||.:........ ....:
  Fly   102 QRRE---PTKGARALILSPTRELAVQTYKFIKELGR-FMELKSILVLGGDSMDSQFSAI-HTCPD 161

Human   137 IIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLF 201
            :|||||||    |......:||.  :.|::.:|.||||||.:|||...:|..|..||..|:|.:|
  Fly   162 VIVATPGR----FLHLCVEMDLK--LNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMF 220

Human   202 SATQTQEVENLVRAGLRNPV--RVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFLRN 264
            |||..:.:....||||.:||  |:.|:         .|.|..|...::.|:.|:::..||..|:.
  Fly   221 SATLPKLLVEFARAGLNDPVLIRLDVE---------SKLPDALALKFLYCRPDDRYTALVVLLKY 276

Human   265 --HKQEKHLVFFRYSSGLCGRGIRDSARMCSTCACVEYYGKALEVLV--KGVKIMCIHGKMKYKR 325
              ..|.:.:||                      |..:::.:.:..::  .|:....::..:....
  Fly   277 VIPVQSQTVVF----------------------AGTQHHVELISYILTEAGISNASVYSSLDPAA 319

Human   326 NKI-FMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVF 389
            .|| ..:|...:..:|:.|||.|||||||.:::|:....|.....||||.||.||.|..|:|...
  Fly   320 RKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLFVHRVGRCARAGRTGTAYSI 384

Human   390 LLPMEESYI--NFLAINQKCPLQEMK-----PQRNTADLLPKLKSMALAD-------RAVFEKGM 440
            :...:.:::  ..|.:|:...:.:..     ||    |||.: :.:.:.|       ..|.....
  Fly   385 VSTDDTAHLLDLHLFLNRPFNIHDSSALGTIPQ----DLLEE-EHLTVTDIKKSHHIAGVLRTSE 444

Human   441 KAFVSYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQFPDF---VPV-----DV 497
            .|:..|:.:......:...|:|.:.|      |||           |...||   .||     :.
  Fly   445 NAYKKYLSSRPVASTDANARVKKIKF------FAL-----------KPLEDFFTAAPVLAQAAEA 492

Human   498 NTDTIPFKDKIREKQRQKLLEQQR----REKTENEGRRKFIKNKAWSKQKA-----KKEKKKK-- 551
            :..:...:.|:...:| ||.|::.    :.::...|...|..|   :.||:     .|||:.:
  Fly   493 SGQSTESQAKVSAAER-KLQEEKHDILVKMRSFRPGGTVFELN---TTQKSTQFIVMKEKRMQHA 553

Human   552 --MNEKRKREEGSDIEDE------------------------------------DMEELLNDTRL 578
              :|:.|::....||::|                                    :|:.|..|...
  Fly   554 EVINKFRQQRAEEDIDEEKKTIEALNPSSGRMPTADEEAISSTFNKVVAPKRLQNMDALYKDKPK 618

Human   579 LKKLKKGKITEEEF----------EKGL-LTTGKRTIKTVDLGISD 613
            .||.|.....|:.:          |.|| :...:|..:..:..:||
  Fly   619 KKKRKINSKDEDHYVPYQSADKHTEDGLAINNFERQAQNAEFSVSD 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX55	XP_016875199.1	SrmB	16..438	CDD:440279	129/442 (29%)
		DEADc_DDX55	20..224	CDD:350718	79/205 (39%)
		DUF4217	423..480	CDD:464056	10/63 (16%)
CG32344	NP_612028.4	DEADc_DDX54	39..243	CDD:350717	80/216 (37%)
		SrmB	41..449	CDD:440279	131/456 (29%)
		DBP10CT	<679..721	CDD:462373