| Sequence 1: | NP_065924.3 | Gene: | LRRN1 / 57633 | HGNCID: | 20980 | Length: | 716 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_729265.1 | Gene: | ltl / 38845 | FlyBaseID: | FBgn0268063 | Length: | 817 | Species: | Drosophila melanogaster |
| Alignment Length: | 638 | Identity: | 134/638 - (21%) |
|---|---|---|---|
| Similarity: | 229/638 - (35%) | Gaps: | 225/638 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Human 19 MTSLTE-----SSIQNSECPQL--CVCEI-RPWFTPQSTYREATTVDCNDLR-----LTRIPSNL 70
Human 71 SSDTQVLLLQSNNIAKTVDELQQL------FNLTELDFSQNNFTNIKEV---GLANLTQLT---- 122
Human 123 ---------------------------------------------------------------TL 124
Human 125 HLEENQITEMTDYCLQDLSNLQELYINHNQISTIS-------------AH---------AFAGLK 167
Human 168 NLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV-------------IGILDMNFKPLANLRS 219
Human 220 LVL-------AGMYLTDIPGNALV---GLDSLESLSFYDNKLVK-------VPQL---------- 257
Human 258 -------ALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGI--NNMGELVSVDRYALDNLPE 313
Human 314 LTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTV-------ESLPNLREISIHSN 371
Human 372 PLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSEQC--LPMISHDSFPNR 434
Human 435 LNVDIGTTVFLDCRAMAEPEPEIYWVTP----------------IGNKITVET 471 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LRRN1 | NP_065924.3 | LRRNT | 32..75 | CDD:214470 | 9/50 (18%) |
| leucine-rich repeat | 54..73 | CDD:275380 | 3/23 (13%) | ||
| LRR 1 | 73..95 | 5/27 (19%) | |||
| leucine-rich repeat | 74..96 | CDD:275380 | 4/27 (15%) | ||
| LRR | <89..355 | CDD:443914 | 91/412 (22%) | ||
| LRR 2 | 96..117 | 8/23 (35%) | |||
| leucine-rich repeat | 97..120 | CDD:275380 | 8/25 (32%) | ||
| LRR 3 | 120..141 | 8/87 (9%) | |||
| leucine-rich repeat | 121..144 | CDD:275380 | 10/89 (11%) | ||
| LRR 4 | 144..165 | 9/42 (21%) | |||
| leucine-rich repeat | 145..168 | CDD:275380 | 10/44 (23%) | ||
| LRR 5 | 168..189 | 6/20 (30%) | |||
| leucine-rich repeat | 169..192 | CDD:275380 | 6/22 (27%) | ||
| LRR 6 | 192..213 | 6/33 (18%) | |||
| leucine-rich repeat | 193..216 | CDD:275380 | 5/35 (14%) | ||
| LRR 7 | 216..237 | 6/30 (20%) | |||
| leucine-rich repeat | 217..240 | CDD:275380 | 8/32 (25%) | ||
| LRR 8 | 240..261 | 8/44 (18%) | |||
| leucine-rich repeat | 241..264 | CDD:275380 | 7/46 (15%) | ||
| LRR 9 | 264..285 | 9/20 (45%) | |||
| leucine-rich repeat | 265..288 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 289..313 | CDD:275380 | 7/25 (28%) | ||
| LRR 10 | 313..335 | 5/21 (24%) | |||
| leucine-rich repeat | 314..335 | CDD:275380 | 5/20 (25%) | ||
| LRR 11 | 338..359 | 6/27 (22%) | |||
| leucine-rich repeat | 339..362 | CDD:275378 | 6/29 (21%) | ||
| leucine-rich repeat | 363..375 | CDD:275378 | 4/11 (36%) | ||
| LRRCT | 371..419 | CDD:214507 | 6/47 (13%) | ||
| I-set | 429..516 | CDD:400151 | 10/59 (17%) | ||
| Ig strand B | 443..447 | CDD:409562 | 1/3 (33%) | ||
| Ig strand C | 456..460 | CDD:409562 | 0/3 (0%) | ||
| Ig strand E | 483..486 | CDD:409562 | |||
| Ig strand F | 496..501 | CDD:409562 | |||
| Ig strand G | 509..512 | CDD:409562 | |||
| FN3 | 531..600 | CDD:214495 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 691..716 | ||||
| ltl | NP_729265.1 | LRR | 65..476 | CDD:443914 | 91/420 (22%) |
| leucine-rich repeat | 65..86 | CDD:275380 | 3/23 (13%) | ||
| leucine-rich repeat | 87..110 | CDD:275380 | 7/22 (32%) | ||
| leucine-rich repeat | 111..134 | CDD:275380 | 2/22 (9%) | ||
| leucine-rich repeat | 135..158 | CDD:275380 | 0/22 (0%) | ||
| leucine-rich repeat | 159..180 | CDD:275380 | 0/20 (0%) | ||
| leucine-rich repeat | 181..203 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 204..226 | CDD:275380 | 6/21 (29%) | ||
| leucine-rich repeat | 227..249 | CDD:275380 | 4/21 (19%) | ||
| leucine-rich repeat | 250..272 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 273..296 | CDD:275380 | 3/22 (14%) | ||
| leucine-rich repeat | 297..315 | CDD:275380 | 4/17 (24%) | ||
| leucine-rich repeat | 320..335 | CDD:275378 | 3/14 (21%) | ||
| leucine-rich repeat | 344..366 | CDD:275380 | 4/21 (19%) | ||
| leucine-rich repeat | 367..391 | CDD:275380 | 3/23 (13%) | ||
| leucine-rich repeat | 392..415 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 416..439 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 440..462 | CDD:275380 | 6/26 (23%) | ||
| leucine-rich repeat | 463..483 | CDD:275380 | 6/19 (32%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||