Protein Alignment STIM2 and stim2

DIOPT Version :10

• Sequence 1: NP_001162589.1
• Gene: STIM2 / 57620
• HGNCID: 19205
• Length: 754
• Species: Homo sapiens
• Sequence 2: XP_004916816.2
• Gene: stim2 / 733739
• XenbaseID: XB-GENE-992607
• Length: 748
• Species: Xenopus tropicalis
• Alignment Length: 711
• Identity: 526/711 - (73%)
• Similarity: 590/711 - (82%)
• Gaps: 36/711 - (5%)

Human    44 DSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNK 108
            |:|||::||..|||||..||:||.||||:.||||||||||||||||||||||:|||:.||||:.|
 Frog    74 DTPALLSDPFNSLSPPVLTEDDRSSLEAICTIHKQMDDDKDGGIEVEESDEFLREDLNYKDASQK 138

Human   109 HSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAV 173
            |:||||||||||:||||.:||||||||||.|:|||||:|||||||||||||:|:||||.||||||
 Frog   139 HNHLHREDKHITVEDLWAQWKTSEVHNWTEEETLQWLLEFVELPQYEKNFRENSVKGTALPRIAV 203

Human   174 HEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQN 238
            :||..|||||||:|||||||.||||||||||||.|||||||:||||||:||||||||||||||||
 Frog   204 NEPVLMISQLKITDRSHRQKFQLKALDVVLFGPPTRPPHNWVKDFILTISIVIGVGGCWFAYTQN 268

Human   239 KTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACR 303
            :|||||:::||||||.||.||.||::||:||||||||||.||||||||||||||||:.||.||.|
 Frog   269 RTSKEHISQMMKDLEGLQKAEISLLELQDRLEKAQEENRTVAVEKQNLERKMMDEISDAKREAHR 333

Human   304 LRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNI 368
            ||||||||||||||.:|||:||.|||||||||||||||||:||||:.||||||||||||||||||
 Frog   334 LRELREGAECELSRLKYAEEELVQVRMALKKAEKEFELRSNWSVPETLQKWLQLTHEVEVQYYNI 398

Human   369 KRQNAEMQLAIAKDEVAASYLIQAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTT 433
            |:|||||.|||||||        ||||||||||||||||||||||||||||||||||||||||||
 Frog   399 KKQNAEMHLAIAKDE--------AEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTT 455

Human   434 CLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPP 498
            ||||||:|||||||:|||.|.||||||:|||:|||||||||||||||||||||||||||||||||
 Frog   456 CLRERLYRWQQIEKMCGFPIVHNSGLPNLTSTLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPP 520

Human   499 IVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLP 563
            |:|||.|::.|..|:|:||||:||.||||||.|||.|:.                        |.
 Frog   521 IISQFHGSIIKTHGTLSRSSSVCRHRRSIVPPSPQSQQI------------------------LQ 561

Human   564 SPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSPPLSLEIYQTL 628
            |||||||||||||||||.||||:||||.|||||...||.||||||:||:||:||   |.|: |.:
 Frog   562 SPDPDILSVSSCPALYRTEEEEDAIYFIAEKQWGTQDTGSECDSLSSSVGRRQS---SFEV-QQV 622

Human   629 SPRKISRDEVSLEDSSRGDSPVTVDVSWGSPDCVGLTETKSMIFSPASKVYNGILEKSCSMNQLS 693
            :.|||||:|.|.|:|..||||...:.....||..||:|::||:||||||||||||||||||:|||
 Frog   623 NARKISREETSCEESLSGDSPSAAEAPKACPDATGLSESQSMVFSPASKVYNGILEKSCSMHQLS 687

Human   694 SGIPVPKPRHTSCSSAGNDSKPVQEAPSVARISSIPHDLCHNGEKSKKPSKIKSLFKKKSK 754
            ..:|.|||......|..||||||||...:..:.:.|.:|..||||:||.||||.|.||.||
 Frog   688 GILPSPKPPLPPFPSNANDSKPVQEVHGIPVVKTTPLELSQNGEKNKKQSKIKVLLKKISK 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STIM2	NP_001162589.1	SAM_STIM2	132..205	CDD:188973	61/72 (85%)
		PRK00409	<250..430	CDD:234750	151/179 (84%)
		SOAR	346..453	CDD:465164	92/106 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	491..570		38/78 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	693..754		29/60 (48%)
stim2	XP_004916816.2	SAM_STIM2	162..235	CDD:188973	61/72 (85%)
		SMC_prok_B	<269..>468	CDD:274008	173/206 (84%)
		SOAR	376..475	CDD:465164	92/106 (87%)