Protein Alignment FNIP2 and CG3764

DIOPT Version :10

• Sequence 1: NP_001353772.1
• Gene: FNIP2 / 57600
• HGNCID: 29280
• Length: 1167
• Species: Homo sapiens
• Sequence 2: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 108/512 - (21%)
• Similarity: 190/512 - (37%)
• Gaps: 136/512 - (26%)

Human    31 DRWTEYSIQTMEPDNLELIFDFFEEDLS---EHVVQGDVLPGHVGTACLLSSTIAESGRSAGILT 92
            :|...||......:|.||.||:..::|:   |.:|.....|.|......:.|.:.:.||:
  Fly   977 ERKFNYSCDITYTNNSELGFDYLRDNLTSNREQLVMRWPKPFHFAIVDEVDSVLIDEGRN----- 1036

Human    93 LPIM-----SRNSRKTIGKVRVDFIIIKPLPGYSCSMQSSFSKYWKPRIPLDVGHRGAGNSTTTA 152
             |::     :.|:.:.....:|..:::|. ..|...::.:..:..:..|.|      |..:..|.
  Fly  1037 -PLLISGEANENAARYPVAAKVAELLVKD-SHYKVELKENSVELTEEGISL------AEMALETG 1093

Human   153 KLAKVQENTIASLRNAASHGAAFVEFDV-HLSKDFVPVVYHDLTCCLTMKRKY-----------E 205
            .|....:.....:.||.. ...|.:.|| ::.:|...::.::||..:..||::           |
  Fly  1094 DLWDENDPWARFVMNALK-AKEFYKRDVQYIVRDGKALIINELTGRVEDKRRWSEGVHQAVEAKE 1157

Human   206 ADPVELFEIPVKELTFDQLQLL--KLSHVT-ALKTKDRKQSLYEEENFFSENQPFPSLKM----V 263
            ...::...|.|.::|:..|..|  |||.:| ..||        ||:.|         |||    |
  Fly  1158 GLEIQADSIVVAQITYQSLFKLYPKLSGMTGTAKT--------EEKEF---------LKMFQIPV 1205

Human   264 LESLPENVGFNIEI------------KWICQH-----RDGVWDGNL----STYFDMNVFLDIILK 307
            :| :|.|:. ||.|            ||  :|     .|....|..    :|..:.:.:|..:||
  Fly  1206 IE-VPTNLS-NIRIDLPIQAFATARGKW--EHVRREVEDMFGQGRPVLVGTTSVENSEYLSELLK 1266

Human   308 T--VLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQ--GK-SDIY----PELMDLRSRTTP 363
            .  :..|....|..:::.:||   .:.|...||.|...|.  |: :||.    |::: .|.....
  Fly  1267 EWGIPHNVLNARPKYAAREAD---FIAQAGRKYAITISTNMAGRGTDIILGGNPKML-AREIIED 1327

Human   364 IAMSFAQFENILGINAHTEDLLR--------NPS-------------YVQEAKAKGLVIFCWGDD 407
            ..:|:...| :|..|...::|.:        .||             ||.::::|.     |
  Fly  1328 SILSYLTSE-VLADNIDDDELSQKVLSKIKVGPSSLALLARASLMAKYVGKSESKS-----W--- 1383

Human   408 TNDPENRRKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQE-----LPELKNC 459
                 .|:|.|......|...:..|.|..|..|.:..::..|...     |..||:|
  Fly  1384 -----TRKKAKSVVTESLEKSQTMDPMELQNLINEQSEMYPLGPAIALAYLSVLKDC 1435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FNIP2	NP_001353772.1	FNIP_N	69..191	CDD:464228	20/127 (16%)
		FNIP_M	350..583	CDD:434087	27/140 (19%)
		FNIP_C	980..1163	CDD:464229
CG3764	NP_001261977.1	FNIP_N	101..226	CDD:464228
		FNIP_M	461..692	CDD:434087
		FNIP_C	1269..1461	CDD:464229	38/185 (21%)