Protein Alignment TAOK1 and SPS1

DIOPT Version :9

• Sequence 1: NP_065842.1
• Gene: TAOK1 / 57551
• HGNCID: 29259
• Length: 1001
• Species: Homo sapiens
• Sequence 2: NP_010811.1
• Gene: SPS1 / 852135
• SGDID: S000002931
• Length: 490
• Species: Saccharomyces cerevisiae
• Alignment Length: 508
• Identity: 160/508 - (31%)
• Similarity: 243/508 - (47%)
• Gaps: 72/508 - (14%)

Human    24 PEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNS 88
            |.||::....||.|:||.||.|.|..|.|:||||.::.  :.|.|..:.:.:|:.||..:|.|..
Yeast    14 PSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNL--EHSDEDIELLAQEIFFLAELKSPLI 76

Human    89 IEYKGCYLREHTAWLVMEYC-LGSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRD 151
            ..|....|.:.:.|:||||| .||.||||: .:...|.|.:::.|.|....||.|||....||||
Yeast    77 TNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRD 141

Human   152 IKAGNILLTEPGQVKLADFG-SASMAS--PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGI 213
            |||.||||.|.|.|||.||| |..:.|  ..::||||||||||||:....:| |:.|.|:|||||
Yeast   142 IKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDG-YNEKADIWSLGI 205

Human   214 TCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKH 278
            |..||.:..|||...:.|..:.::.:.:.|.|| ..:||..::||..||.|.|.|||::..||..
Yeast   206 TTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQ-GPFSDAAKDFVAGCLVKTPADRPSAYNLLSF 269

Human   279 IFVLRERPETVL-----IDLIQRTKDAVRELDNLQYRKMKKLLFQEA--HNGPAVEAQEEEEEQD 336
            .||   :..|:.     :|||::.|  |:|    :|.|:.|...|..  .|...|..:|....:.
Yeast   270 EFV---KNITITNLKSDVDLIKQKK--VQE----RYTKVPKYPLQNRLYKNSNTVRGKEFWNFES 325

Human   337 HGVGRTGTVNSVGSNQSIPSMSISASSQSSSVNSLPDVSDDKSELDMMEGDHTVMSNSSVIHLKP 401
            ..:..|    .:...:..|   |:..|.:||:|              ||..:.:...:......|
Yeast   326 TRLSTT----QISKEELSP---ITQDSPTSSLN--------------MESPYLLHGQTVTPITNP 369

Human   402 EEENYR---------------EEGDPRTRASDPQSPPQVSRHKSHYRNR------EHFATIRT-A 444
            ...::|               :.|.|..:| :.:..|..:.:|.|.:|.      |.|..::. .
Yeast   370 SSSSFRKCTQPVFELDSGMDIDSGCPNAQA-ETEIVPLSNHNKKHKKNDIQALKIEKFDYLKNIV 433

Human   445 SLVTRQMQEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLD 497
            |.:..:|.:..:|.|.|:.::   .|.:|..|....:....:..::|..||::
Yeast   434 SHILNRMYDRARDDETRKYVN---EMLKQFIKTEANVPGFNEVFIEEISLRIE 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAOK1	NP_065842.1	STKc_TAO1	2..318	CDD:270805	125/303 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..433		19/123 (15%)
		SbcC	<442..>877	CDD:223496	11/57 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	567..587
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	911..1001
SPS1	NP_010811.1	STKc_MST3_like	16..291	CDD:270786	118/281 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910