back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment IGSF9 and CG33543

DIOPT Version :9

Sequence 1:	NP_001128522.1	Gene:	IGSF9 / 57549	HGNCID:	18132	Length:	1179	Species:	Homo sapiens
Sequence 2:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	565	Identity:	109/565 - (19%)
Similarity:	169/565 - (29%)	Gaps:	201/565 - (35%)

- Green bases have known domain annotations that are detailed below.

Human   131 TVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVT---------------------WK-LR 173
            |..:||....|||.     .|:|.|          |.:|                     |: .|
  Fly    35 TGGAPPDRPPTPPL-----SLQPST----------PSITHFVNESFIIFCQTVQKDIDTKWRDPR 84

Human   174 GKDLGQGQGQVQVQNGT-----LRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPP 233
            |:.....:|:|.::..|     |....:.....|.:||:.:.....
  Fly    85 GQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNG------------------- 130

Human   234 KNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGC 298
             |..||..::. ||                                     |..||..|....|.
  Fly   131 -NRNVNVEREF-LA-------------------------------------SFELLVNQKISFGK 156

Human   299 YTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANP-PLLFVSWTKDGK 362
            ...|.|                             :..|...::.|.|...| |  .|||..:|:
  Fly   157 TEQVQS-----------------------------VREGRDAMVNCFVEGMPAP--EVSWLYNGE 190

Human   363 ALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPKEE 427
            .:........::.:.|..|..:...|| |||:|.......|...|....:||:     |:.....
  Fly   191 YINTVNSTKHNRLSNGLYIRNVSQADA-GEYTCRAMRITPTFSDSDQITILLR-----IQHKPHW 249

Human   428 YFQE--------VGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQ----VDSNSSLILRPLTKEA 480
            :|.|        ||..:.:.|.|.|:|||..:|....:|:.|...    .|..::|.|:......
  Fly   250 FFNETLPVQYAYVGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHRIFVADYGATLQLQMKNASQ 314

Human   481 HGHWECSASNAVA-----------------RVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWE 528
            .|.::|..:|.:.                 |......:|..|....:.|       |:.:|||.|
  Fly   315 FGDYKCKVANPLGMLERVIKLRPGPKPLGPRRFQLKKLYTNGFELDIQT-------PRMSNVSDE 372

Human   529 P---GFDGGYLQ----RFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLA 586
            .   |:...|:.    :||......||:.|...|         |..|.::|.|:.:|.|.....:
  Fly   373 MQIYGYRVAYMSDTEFKFSAGNWSYAKQRDFSFH---------GGKHFIIPHLETNTTYLMRAAS 428

Human   587 QNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLSPPRGLV 631
            :|..|...:|      |..:.||.|.....|.     |.|..||:
  Fly   429 RNLAGLSDWS------PVKVFTTAAGCSWSPW-----LYPSYGLI 462

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.