Protein Alignment KCTD16 and Ktl

DIOPT Version :10

• Sequence 1: NP_065819.1
• Gene: KCTD16 / 57528
• HGNCID: 29244
• Length: 428
• Species: Homo sapiens
• Sequence 2: NP_650926.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 116/262 - (44%)
• Similarity: 160/262 - (61%)
• Gaps: 41/262 - (15%)

Human    24 PEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDY 88
            ||::||||||..|.|..:||:....:||.::|...||:   ||||||||:|:||||.|||||||:
  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDS---LAKDSKGRYFLDRDGVLFRYILDF 63

Human    89 LRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPP 153
            |||:.:.||:.|.|:.||.||||:|:|..:::.:..:.                    |.|  ||
  Fly    64 LRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSER--------------------DAR--PP 106

Human   154 SSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDR- 217
                      |.||:|||||...|::|.||.|||::.|||||||::..:||||:|||||||||.
  Fly   107 ----------GCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHG 161

Human   218 APERYTSRFYLKFKHLERAFDMLSECGFHMV-ACNSSVTASFINQY----TDDKIWSSYTEYVFY 277
            ..:||||||:||..::|:|||.|.:.|:.|. :|.|....|.....    |::..|:.|.|:||.
  Fly   162 GTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFI 226

Human   278 RE 279
            |:
  Fly   227 RD 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCTD16	NP_065819.1	BTB_POZ_KCTD16	23..125	CDD:349706	52/100 (52%)
		H1_KCTD16	160..280	CDD:409030	60/126 (48%)
Ktl	NP_650926.1	BTB_POZ_KCTD8-like	1..99	CDD:349676	52/99 (53%)
		H1_KCTD12-like	106..227	CDD:409026	60/130 (46%)