Protein Alignment KCTD16 and twz

DIOPT Version :10

• Sequence 1: NP_065819.1
• Gene: KCTD16 / 57528
• HGNCID: 29244
• Length: 428
• Species: Homo sapiens
• Sequence 2: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 64/281 - (22%)
• Similarity: 113/281 - (40%)
• Gaps: 65/281 - (23%)

Human    18 AVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLF 82
            |..:.:...|.::|||.:|.:...||...|.|.|.|:|:.:.....|..|.   .:||||||.:|
  Fly   128 AAASRYTAPVHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQ---HYFIDRDGGMF 189

Human    83 RYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSD 147
            |:||:::|:.::::.:.||:...|..||.|:::..::|.|             .|..:|..:..:
  Fly   190 RHILNFMRNSRLLIAEDFPDLELLLEEARYYEVEPMIKQL-------------ESMRKDRVRNGN 241

Human   148 TRICPP---------SSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKE 203
            ..:.||         |....|..:..:..|....|..||.            ||::....:|..|
  Fly   242 YLVAPPTPPARHIKTSPRTSASPECNYEVVALHISPDLGE------------RIMLSAERALLDE 294

Human   204 VFGETLNESRDPDRAPERYTS-------RF----YLKFKHLERAFDMLSECGFHMVACNSSVTAS 257
            :|.|. :::....|:...:..       ||    |.|...:: ....|...||       ::.||
  Fly   295 LFPEA-SQATQSSRSGVSWNQGDWGQIIRFPLNGYCKLNSVQ-VLTRLLNAGF-------TIEAS 350

Human   258 FINQYTDDKIWSSYTEYVFYR 278
            ...|        .::||:..|
  Fly   351 VGGQ--------QFSEYLLAR 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCTD16	NP_065819.1	BTB_POZ_KCTD16	23..125	CDD:349706	33/101 (33%)
		H1_KCTD16	160..280	CDD:409030	24/130 (18%)
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	33/108 (31%)