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Protein Alignment ADGRB1 and AdamTS-B

DIOPT Version :9

Sequence 1:	XP_016869180.1	Gene:	ADGRB1 / 575	HGNCID:	943	Length:	1663	Species:	Homo sapiens
Sequence 2:	NP_572247.2	Gene:	AdamTS-B / 31490	FlyBaseID:	FBgn0029791	Length:	1023	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	130/549 - (23%)
Similarity:	165/549 - (30%)	Gaps:	182/549 - (33%)

- Green bases have known domain annotations that are detailed below.

Human   162 PPGPTDDFSVEYLVVGNRNPSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAA- 225
            ||.|.|:::....:.|.|..:|..|:     |...|........|......|:.|..:..|...
  Fly   520 PPTPLDEYNYTGELPGMRYNARGQCR-----LQFNLTTDSEVGACSAPHEFCSTLWCKVNGECVT 579

Human   226 --GPLAPRGDVCLRDAVAGGPENCLTSLTQDRGGHGA-TGGWKLWSLWGECTRDCGGGLQTRTRT 287
              .|.|| |.:|      |..:.|.......|....| .|||..||.|.||:|.||||:.|:.|.
  Fly   580 HMRPTAP-GTLC------GRNKWCQNGKCVRREELAAVNGGWGDWSEWSECSRSCGGGVSTQQRE 637

Human   288 C-LPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQ 351
            | .|.|...|..|.|..:..:.|.:..| ||...|.|:|..    ||     .|.:...|
  Fly   638 CDNPVPANGGVFCIGERKRYKICRKRPC-PAEEPSFRAQQC----AR-----FDNVSYQG----- 687

Human   352 TGDPAAEEWSPW----SVCSSTCGE-------GW------------------------------- 374
                |..:|.|:    :.|...|.:       .|
  Fly   688 ----ATYKWLPFFDKNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGICKKVGCDWI 748

Human   375 ------QTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEW-----------------S 416
                  ..|...|..|  ..||. |:||   ..........||:.|.                 |
  Fly   749 VDSEVQDDRCGVCGGS--GDQCQ-PVRE---TYTDPFAAKDGAYVEIVTIPARARHILIRELANS 807

Human   417 PWSLCSSTCGRGFR---------------------------DRTRTCRPPQFGGNPCE------- 447
            |..|..:|...|.|                           |...|...||    |.:
  Fly   808 PHFLAIATGDGGDRFYLNGDSLISMPGEFEIAGAESLYDRVDEQETITIPQ----PIQHSISLYA 868

Human   448 ---GPEKQTK-FCNIALCPGRAVDGNWNEW--SSWSACSASCSQGRQQRTREC--NGPSYGGA-E 503
               |.|.... |....|.......|...:|  |:|:||||||..|.|.|...|  ||.:.|.. .
  Fly   869 IVRGNESNAGIFYEFTLPALNVTAGRQFQWRLSNWTACSASCGGGVQHREPICQENGKALGDTLP 933

Human   504 CQGHWV------ETRDCFLQQCPVDGKWQAW-ASWGSCSVTCG-----AGSQRRERVCSGPFFGG 556
            |..|..      ::|.|..|.||  ..|  | ..|..|.|||.     |..|||..|
  Fly   934 CWTHAKNKRPARQSRGCGDQPCP--AHW--WPGPWQFCPVTCRPVGFVAPPQRRRSV-------- 986

Human   557 AACQGPQDEY---RQCGTQRCPEPHEICD 582
             .|....|..   .:||..:.|...|.|:
  Fly   987 -VCLDEHDVVVADAECGHLQKPAEMEPCE 1014

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.