Protein Alignment MRTFB and mrtfb

DIOPT Version :10

• Sequence 1: NP_001295071.1
• Gene: MRTFB / 57496
• HGNCID: 29819
• Length: 1099
• Species: Homo sapiens
• Sequence 2: XP_012826015.1
• Gene: mrtfb / 780107
• XenbaseID: XB-GENE-487634
• Length: 1079
• Species: Xenopus tropicalis
• Alignment Length: 1118
• Identity: 700/1118 - (62%)
• Similarity: 840/1118 - (75%)
• Gaps: 58/1118 - (5%)

Human     1 MDHTGAIDTEDEVGPLAHLAPSPQSEAVAHEFQELSLQSSQNLPPLNERKNVLQLRLQQRRTREQ 65
            |:|..|.|.|:|.|.|..||.|||||||||:||||||||.|.||||.||||||||||||||||||
 Frog     1 MNHHMAQDMEEEPGSLLSLASSPQSEAVAHDFQELSLQSVQQLPPLKERKNVLQLRLQQRRTREQ 65

Human    66 LVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQM 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||:
 Frog    66 LVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETLAEPSLQATQL 130

Human   131 KLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVGKEDYPHTQGDFSFDEDSSDAL 195
            |||||||||||||||||||||:|||||||||||.||||||. |.:.::|......||||||||||
 Frog   131 KLKRARLADDLNEKIAQRPGPLELVEKNILPVDLSVKEAIT-VSQTNFPENLDTLSFDEDSSDAL 194

Human   196 SPDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEFLKTPPTADQPPPRPAAPV 260
            ||:||||||||||||||.|.|.|.|.||: :||..|..:||..:|:|.|..||||.....|.:.
 Frog   195 SPEQPASQESQGSAASPGEIKTSGSSSPI-SNTTIQCQTVSSPLPDFFKPSPTADLTTRSPLSS- 257

Human   261 LPTNTVSSAKPGPALVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQMDSN 325
                  |..||||||:||:..|:. :|.||||.||||||||||||||||||||||||.|.:||||
 Frog   258 ------SVCKPGPALIKQTQSKHA-EKPRSKKSKDPKPRVKKLKYHQYIPPDQKGEKVEAEMDSN 315

Human   326 YARLLQQQQLFLQLQILSQQKQHYNYQTILPAPFKPLNDKNS-NSGNSALNNATP----NTPRQN 385
            ||||||||||||||||||||:||||:|.|||||.|.|..:|| |:..|.:|.:.|    :..|||
 Frog   316 YARLLQQQQLFLQLQILSQQQQHYNFQKILPAPLKSLKKQNSINTTTSNVNASIPSVQCSVSRQN 380

Human   386 TSTPVRKPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVNSSGLA--AGGIVA 448
             |.|.:|.|||||:|||:||:|||.|||||||||||||.||||||||:|:.:|:|:|  :|.||.
 Frog   381 -SVPSKKTGPLPSNLDDMKVAELKMELKLRGLPVSGTKMDLIERLKPFQDFSSNGVAPNSGNIVT 444

Human   449 VSSSAIVTSNPEVTVALPVTTLHNTV--TSSVSTLKAELPPTGTSNATRVENVHSPLPISPSPSE 511
            ::::|..|:. :.||....:.|.|:.  |.|||: .|.:...| :|.|.::.::||||:||:|||
 Frog   445 IATTACSTTE-DATVVFSTSALMNSCSPTPSVSS-DASILSVG-NNQTALDGINSPLPMSPAPSE 506

Human   512 QSSLSTDDTNMADTFTEIMTMMSPSQFLSSSPLRMTNNEDSLSPTSSTLSNLELDAAEKDRKLQE 576
            ||:.|::|||:.|||.|||||||||||:::|||::..||||:..|:...:|:||||.||||||||
 Frog   507 QSNFSSEDTNITDTFAEIMTMMSPSQFMNTSPLKVILNEDSMGATNGNTTNMELDAVEKDRKLQE 571

Human   577 KEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQQRPLEAQPSAPGHSVKSDQKHGSLGSSIKDE 641
            ||||||:||||||||||||||||.|||:|||||||:|      .|...:|.:.||.:|  .||:|
 Frog   572 KEKQIEDLKRKLEQEQKLVEVLKKQLELEKRGQQQQP------CPNVLLKVEPKHFNL--QIKEE 628

Human   642 ASLPDCSSSRQPIPVASHAVGQP-VSTGGQTLVAKKAVVIKQEVPVGQAEQQSVVSQFYVSSQGQ 705
            .:.|||.:::|.:..:...:||| .:|..|.::|..|:|||.|||:.:::.|:|:.||||:||..
 Frog   629 TAAPDCQNAKQSLVSSGQIIGQPTAATISQNIIANNALVIKHEVPLAKSDHQNVIQQFYVTSQRP 693

Human   706 PPPAVVAQPQALLTTQTAQLLLPVSIQGSSVTSVQLPVGSLKLQTSPQAGMQTQPQIATAAQIP- 769
            |..||||||||||.||||||||||||:..:  .|||.:            :|.||...:.|..|
 Frog   694 PQTAVVAQPQALLATQTAQLLLPVSIKAPN--GVQLSM------------VQAQPHTVSPAPTPL 744

Human   770 --TAALASGL-AP---TVPQTQDTFPQHVLSQPQQVRKVFTNSASSNTVLPYQRHPAPAVQQPFI 828
              |||..|.: ||   ..|..||.|.||:|:|.||:||: ..||:|..|..|.::|..||.|.|.
 Frog   745 STTAATTSLVQAPQKQPAPLAQDKFTQHLLNQNQQIRKL-CPSATSGNVFSYPQNPVIAVPQSFS 808

Human   829 NKASNSVLQSRNAPLPSLQNGPNTPNKPS-SPPPPQQFVV-QHSLFGSPVAKTKDPPRYEEAIKQ 891
            ...|.:....||..:.::||||.:..:.| :||.||||:| ||.:|..|..|:||||||||||||
 Frog   809 ASLSANAQPQRNTQIAAMQNGPTSLQEESPTPPQPQQFIVQQHPVFSGPTTKSKDPPRYEEAIKQ 873

Human   892 TRSTQAPLPEISNAHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTASITTMPVNTVVSRP 956
            .|:..|..||:|||||||||||||||||||||| |:.:|||||||||||||::||||||||||||
 Frog   874 ARNNPASQPEVSNAHSQQMDDLFDILIKSGEIS-PLIKEPSPISKMRPVTANVTTMPVNTVVSRP 937

Human   957 PPQVQMAPPVSLEPMGSLSASLENQLEAFLDGTLPSANEIPPLQSSSEDREPFSLIEDLQNDLLS 1021
            |||:.:|||::||...|||.|||:||||||||||||.|.||.|:|:|:|||.||||:||.||||.
 Frog   938 PPQIHVAPPLTLESTNSLSVSLESQLEAFLDGTLPSENNIPHLESNSDDRETFSLIDDLNNDLLQ 1002

Human  1022 HSGMLDHSHSPMETSETQFAAGTPCLSLDLSDSNLDNMEWLDITMPNSSSGLTPLSTTAPSMFSA 1086
            :||||||..:|||||:|.|.|.: ||||||:|:|||||||||:|||||:|.|||||:|.|||||.
 Frog  1003 NSGMLDHDSAPMETSDTPFTANS-CLSLDLADANLDNMEWLDLTMPNSASSLTPLSSTLPSMFST 1066

Human  1087 DFLDPQDLPLPWD 1099
            ||||..||.|.|:
 Frog  1067 DFLDSNDLQLHWE 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRTFB	NP_001295071.1	RPEL	52..76	CDD:475195	23/23 (100%)
		RPEL	96..119	CDD:460677	22/22 (100%)
		RPEL	139..164	CDD:128947	23/24 (96%)
		PHA03247	<197..410	CDD:223021	134/217 (62%)
		SAP	400..433	CDD:460424	28/32 (88%)
		DUF2130	568..>603	CDD:430914	31/34 (91%)
		SP1-4_N	<649..>826	CDD:425404	79/184 (43%)
mrtfb	XP_012826015.1	RPEL	52..76	CDD:475195	23/23 (100%)
		RPEL	96..119	CDD:460677	22/22 (100%)
		RPEL	140..163	CDD:460677	21/22 (95%)
		SAP	394..427	CDD:460424	28/32 (88%)
		COG2433	<563..>602	CDD:441980	34/38 (89%)
		PHA03247	<693..936	CDD:223021	140/258 (54%)