Protein Alignment MRTFB and Mrtfb

DIOPT Version :10

• Sequence 1: NP_001295071.1
• Gene: MRTFB / 57496
• HGNCID: 29819
• Length: 1099
• Species: Homo sapiens
• Sequence 2: XP_006522171.1
• Gene: Mrtfb / 239719
• MGIID: 3050795
• Length: 1112
• Species: Mus musculus
• Alignment Length: 1126
• Identity: 922/1126 - (81%)
• Similarity: 978/1126 - (86%)
• Gaps: 41/1126 - (3%)

Human     1 MDHTGAIDTEDEVGPLAHLAPSPQSEAVAHEFQELSLQSSQNLPPLNERKN-------------- 51
            ||||||||||:|:|||||||||||||:||||||||||||||:||.||||||
Mouse     1 MDHTGAIDTEEELGPLAHLAPSPQSESVAHEFQELSLQSSQHLPTLNERKNGSIVFGESGLQLPL 65

Human    52 -------VLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSE 109
                   ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 PAQSVSTVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSE 130

Human   110 LVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVG 174
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.
Mouse   131 LVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVV 195

Human   175 KEDYPHTQGDFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTV 239
            |||||||.|:||||||||||||||||||||||||||||||||||.||.|||.:|||||.||||.|
Mouse   196 KEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTASTPAQFTSVSPAV 260

Human   240 PEFLKTPPTADQPPPRPAAPVLPTNTVSSAKPGPALVKQSHPKNPNDKHRSKKCKDPKPRVKKLK 304
            |||||||.||||||.|..|||||||||||||.||.||||||||||||||||||||||||||||||
Mouse   261 PEFLKTPLTADQPPTRSTAPVLPTNTVSSAKSGPMLVKQSHPKNPNDKHRSKKCKDPKPRVKKLK 325

Human   305 YHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILS-----QQKQHYNYQTILPAPFKPLND 364
            |||||||:|||||:|||||||||||||||||||||||||     ||:||||||||||||.|  .|
Mouse   326 YHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIK--TD 388

Human   365 KNSNSGNSALNNATPNTPRQNTSTPVRKPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIER 429
            |||:||:::         ..::|.|.|:|||||||||||||||||||||||||||||||||||||
Mouse   389 KNSSSGSNS---------GSSSSMPARRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIER 444

Human   430 LKPYQEVNSSGLAAGGIVAVSSSAIVTSNPEVTVALPVTTLHNTVTSSVSTLKAELPPTGTSNAT 494
            |||||||.||.||.|.||||||:.|||||||||||||||||||.|||||||.||:|....||:..
Mouse   445 LKPYQEVTSSNLATGSIVAVSSATIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLALPATSSVP 509

Human   495 RVENVHSPLPISPSPSEQSSLSTDDTNMADTFTEIMTMMSPSQFLSSSPLRMTNNEDSLSPTSST 559
            .|||.|||||||||||||||||||||||.||||||||||||||.|.|||||:.:::|||||:|||
Mouse   510 HVENAHSPLPISPSPSEQSSLSTDDTNMTDTFTEIMTMMSPSQLLCSSPLRVVSHDDSLSPSSST 574

Human   560 LSNLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQQRPLEAQPSAPGHS 624
            ||.|||||||||||||||||||||||||||||||||||||||||||||| ||||.:.|||.|.|.
Mouse   575 LSTLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRG-QQRPPDPQPSDPPHP 638

Human   625 VK-SDQKHGSLGSSIKDEASLPDCSSSRQPIPVASHAVGQPVSTGGQTLVAKKAVVIKQEVPVGQ 688
            .. ||.||||:|||||||||||||||.:|||.|..|:||||:|||.|||||||.||:|||||:.|
Mouse   639 FNTSDPKHGSVGSSIKDEASLPDCSSPQQPITVPGHSVGQPISTGSQTLVAKKTVVVKQEVPMAQ 703

Human   689 AEQQSVVSQFYVSSQGQPPPAVVAQPQALLTTQTAQLLLPVSIQGSSVTSVQLPVGSLKLQTSPQ 753
            ||||:||||||:||||| |||:||||||||||||.|||||||||||:|||||||||||:|||..|
Mouse   704 AEQQNVVSQFYLSSQGQ-PPALVAQPQALLTTQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAQ 767

Human   754 AGMQTQPQIATAAQIPTAALASGLAPTVPQTQDTFPQHVLSQPQQVRKVFTNSASSNTVLPYQRH 818
            ..:|.||.:|.|.|:|.|||.|.|...:||.|:.||||||.|||.||||||||| .||||.|||.
Mouse   768 GRVQAQPHVAAATQVPAAALPSALTSALPQKQEAFPQHVLGQPQPVRKVFTNSA-PNTVLQYQRQ 831

Human   819 PAPAVQQPFINKASNSVLQSRNAPLPSLQNGPNTPNKPSSPPPPQQFVVQHSLFGSPVAKTKDPP 883
            |.|..||||::|.||..||||.|||..|||||:..:||||||||||||||||||.:|:.||||||
Mouse   832 PGPTNQQPFVSKTSNPALQSRTAPLAPLQNGPSLASKPSSPPPPQQFVVQHSLFATPITKTKDPP 896

Human   884 RYEEAIKQTRSTQAPLPEISNAHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTASITTMP 948
            ||||||||.||||..|||:|:.|||||||||||||||||||.||||||||||||:||||||||||
Mouse   897 RYEEAIKQARSTQPALPEVSSVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMKPVTASITTMP 961

Human   949 VNTVVSRPPPQVQMAPPVSLEPMGSLSASLENQLEAFLDGTLPSANEIPPLQSSSEDREPFSLIE 1013
            |||||||||||||:||||||||:.|||||||||||||||||||||.:..|||:||||||.|||||
Mouse   962 VNTVVSRPPPQVQIAPPVSLEPVNSLSASLENQLEAFLDGTLPSATDTGPLQNSSEDRESFSLIE 1026

Human  1014 DLQNDLLSHSGMLDHSHSPMETSETQFAAGTPCLSLDLSDSNLDNMEWLDITMPNSSSGLTPLST 1078
            ||||||||||.||..|||||||||.|..:|||||||||||||||||||||||||.:|||||||||
Mouse  1027 DLQNDLLSHSSMLYQSHSPMETSEAQLVSGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLST 1091

Human  1079 TAPSMFSADFLDPQDLPLPWD 1099
            |||||||||||||||||||||
Mouse  1092 TAPSMFSADFLDPQDLPLPWD 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRTFB	NP_001295071.1	RPEL	52..76	CDD:475195	23/23 (100%)
		RPEL	96..119	CDD:460677	22/22 (100%)
		RPEL	139..164	CDD:128947	24/24 (100%)
		PHA03247	<197..410	CDD:223021	173/217 (80%)
		SAP	400..433	CDD:460424	32/32 (100%)
		DUF2130	568..>603	CDD:430914	34/34 (100%)
		SP1-4_N	<649..>826	CDD:425404	127/176 (72%)
Mrtfb	XP_006522171.1	RPEL	73..97	CDD:475195	23/23 (100%)
		RPEL	117..140	CDD:460677	22/22 (100%)
		RPEL	160..185	CDD:128947	24/24 (100%)
		PHA03247	<218..342	CDD:223021	109/123 (89%)
		SAP	415..448	CDD:460424	32/32 (100%)
		DUF2130	583..>618	CDD:430914	34/34 (100%)