Protein Alignment TBC1D24 and Tbc1d24

DIOPT Version :10

• Sequence 1: NP_001186036.1
• Gene: TBC1D24 / 57465
• HGNCID: 29203
• Length: 559
• Species: Homo sapiens
• Sequence 2: XP_038941277.1
• Gene: Tbc1d24 / 287110
• RGDID: 1306143
• Length: 562
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 523/562 - (93%)
• Similarity: 543/562 - (96%)
• Gaps: 3/562 - (0%)

Human     1 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIRDIPCR 65
            |||||||||||||||||:|||||||||:.||||||||||||||||||||||||||||||||||||
  Rat     1 MDSPGYNCFVDKDKMDASIQDLGPKELNYTELQELKQLARQGYWAQSHALRGKVYQRLIRDIPCR 65

Human    66 TVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISF 130
            |||||||||||||||||||||||.|||||||||||||:||||.||||||||||||:|||||||||
  Rat    66 TVTPDASVYSDIVGKIVGKHSSSSLPLPEFVDNTQVPTYCLNPRGEGAVRKILLCIANQFPDISF 130

Human   131 CPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAH 195
            |||||||||||||||||||||||||||||:|||||::||||||||||||||||||||||||||||
  Rat   131 CPALPAVVALLLHYSIDEAECFEKACRILSCNDPGKKLIDQSFLAFESSCMTFGDLVNKYCQAAH 195

Human   196 KLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQPL 260
            ||||||||||||||:||||||||||||.|||||||||||||||||||||||||||||||||||||
  Rat   196 KLMVAVSEDVLQVYSDWQRWLFGELPLNYFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQPL 260

Human   261 ESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEIQLLQMANEKALKQKGITVKQKSVSL 325
            |||:||||||.||:|||||||||||||||||||||||||||||||||||||:|||||||||||||
  Rat   261 ESDNVKQDIRMFVKDIAKTVSPEKLLEKAFAIRLFSRKEIQLLQMANEKALRQKGITVKQKSVSL 325

Human   326 SKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHE 390
            ||||||||||||||||||||||:||||||||:||||||||||||||||||||||:||||||||||
  Rat   326 SKRQFVHLAVHAENFRSEIVSVKEMRDIWSWIPERFALCQPLLLFSSLQHGYSLSRFYFQCEGHE 390

Human   391 PTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKP 455
            ||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||.
  Rat   391 PTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLSFFGTGECFVFRLQPEVQRYEWVVIKHPELTKA 455

Human   456 PPLMAAEPTAP---LSHSASSDPADRLSPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALY 517
            ....::|..|.   :|||.|||||||||||||||||||||||||||||||:||||:|||||||||
  Rat   456 ASFKSSEAAANPCLISHSVSSDPADRLSPFLAARHFNLPSKTESMFMAGGNDCLIIGGGGGQALY 520

Human   518 IDGDLNRGRTSHCDTFNNQPLCSENFLIAAVEAWGFQDPDTQ 559
            ||||||||||.|||||||||||||:|||||||||||||||||
  Rat   521 IDGDLNRGRTGHCDTFNNQPLCSESFLIAAVEAWGFQDPDTQ 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D24	NP_001186036.1	RabGAP-TBC	48..253	CDD:459855	195/204 (96%)
		TLDc	342..554	CDD:214733	191/214 (89%)
Tbc1d24	XP_038941277.1	RabGAP-TBC	48..253	CDD:459855	195/204 (96%)
		TLDc	342..557	CDD:214733	191/214 (89%)