Protein Alignment GATAD2B and simj

DIOPT Version :10

• Sequence 1: XP_047282071.1
• Gene: GATAD2B / 57459
• HGNCID: 30778
• Length: 594
• Species: Homo sapiens
• Sequence 2: NP_001261685.1
• Gene: simj / 39212
• FlyBaseID: FBgn0010762
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 692
• Identity: 210/692 - (30%)
• Similarity: 292/692 - (42%)
• Gaps: 198/692 - (28%)

Human    48 ALLKRKDL-------ANLEV-PHELPTKQDGSGVKGYEEKLNG-------NLRPHGDNRTAGRPG 97
            |.|..:||       |.|.: |...|...:|:.........|.       |...:..:.|.....
  Fly    31 AALSNRDLRALTANNAGLTITPSASPATNNGTTSNSSNTNSNSSSTTTTTNNNNNSSSNTNSSSA 95

Human    98 KENINDEPVDMS-------------------------ARRSEPERGRLTPSPDIIVLS------- 130
            ..|.|:..::.|                         ..|:||:  ....:|||::|.
  Fly    96 NNNNNNNSINASDGVTGATSGSIGGGQDENKVQRRVLRPRTEPK--SYAEAPDIVLLPARTNGRQ 158

Human   131 -----DNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQS 190
                 |:|...       ||......::......::||::.:::||.:||.||.:|:|||||:||
  Fly   159 QNGNIDSETDD-------EEMPPYVPIKELSHAELKEREKSLRKLRQDLRNEETKLMLLKKLKQS 216

Human   191 -QLQKEN-VVQKTPVVQN--------------AASIVQ----PSPAHVGQQGLSKLPSRPG-AQG 234
             |:.||| ||..|.|..|              :.|:..    |.||| .:...|.|....| |..
  Fly   217 QQVMKENLVVTPTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAH-SKGSRSSLSGSGGPAVS 280

Human   235 VEPQNLRTLQGHSVI---------------RSATNTTLP---HMLMSQRVIAP----NPAQLQGQ 277
            :...|.||....|..               ||.:|:.||   ..|.:...:|.    .||.....
  Fly   281 ISATNSRTGSSSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSSSH 345

Human   278 RG---PPKPGLVRTTTPNM--NPAINYQPQSS-------SSVPCQRTTSSAIYMNLA-----SHI 325
            |.   ||     ||..||:  .|::...|.|:       .:||  .|.|:::.:..|     ||.
  Fly   346 RSSNLPP-----RTNLPNLTITPSVTITPTSAPPSSLKPRNVP--GTISNSVSITPALPLSQSHQ 403

Human   326 QPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFI 390
            ......:.....|...|.| .|..|||||:|||||||||||:|||||||.|.:||:|:.:|::|:
  Fly   404 NQHNDQKNDRSTPREDAQT-PAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIPNPSNTDFV 467

Human   391 YMVGLEEVVQSV-IDSQGKSCASLLRVEPFVCAQCRTDFTPHWKQE----KNGKILCEQCMTSNQ 450
            |::|||.||..: ::.:..:.|:     ||.||||:.||||.||.|    |:.|::||||:|||.
  Fly   468 YLLGLETVVDYLTVNKKANAVAA-----PFRCAQCKIDFTPVWKWEKQTNKDPKVICEQCVTSNV 527

Human   451 KKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPT------------TAPAVSSVS----- 498
            |||||||||||||.||||||||||||||||..|::.||.            :..||||.|
  Fly   528 KKALKAEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSSNSSSSHM 592

Human   499 --KQETIMRHH---------------------------TLRQAPQPQSSLQRGIPTSARSMLS-- 532
              ::|.:...|                           |.|..|.|..|.....|:|..|..|
  Fly   593 QREREQLQASHASAAAALVNLPPSVTVIPTKCQTPTPATPRPTPPPPQSQATPPPSSGGSRSSRA 657

Human   533 --NFAQAPQLSVPGGLLGMPGVNIAYLNTGIGGHKGPSLADR 572
              ..|.|...:...|:|. ||.:.|:       |..|:.:.|
  Fly   658 AATAAAAAIAAQQAGILS-PGPSPAH-------HHEPTTSSR 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GATAD2B	XP_047282071.1	P66_CC	160..198	CDD:465178	20/39 (51%)
		GATA	421..455	CDD:425605	23/37 (62%)
simj	NP_001261685.1	P66_CC	185..225	CDD:465178	20/39 (51%)