DRSC/TRiP Functional Genomics Resources

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Protein Alignment DSCAML1 and DIP-zeta

DIOPT Version :9

Sequence 1:XP_011541219.1 Gene:DSCAML1 / 57453 HGNCID:14656 Length:2065 Species:Homo sapiens
Sequence 2:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster


Alignment Length:621 Identity:136/621 - (21%)
Similarity:198/621 - (31%) Gaps:217/621 - (34%)


- Green bases have known domain annotations that are detailed below.


Human   464 GSHRTNQYTMSDGTTISHMNVTGPQIRDGG--VYRCTARNLVGS------------AEYQARINV 514
            |.|.:...|::.|...:.....|.....||  ....|...:|||            ......|.|
  Fly    46 GKHPSGSKTVATGVVPNFGGAAGNGAGGGGPVAGSGTGSTVVGSNGVIVAGGGANVPTSNLNIVV 110

Human   515 RGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWY---KDALLLPDNHRQVVFENGTLKLTDV 576
            ..|.....:.|:|..|||:..:.|.|.....|.:.|.   :.|:|...||  |:..|        
  Fly   111 EEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNH--VITRN-------- 165

Human   577 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRIT 641
                            |::|::...|...:                                  |
  Fly   166 ----------------PRISVTHDKHDRHR----------------------------------T 180

Human   642 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQ---LIVRVPPR 703
            |                      .|.|::|..:..|.|.|..:    ||:.:.|   |.|.|||.
  Fly   181 W----------------------YLHINNVHEEDRGRYMCQIN----TVTAKTQFGYLNVVVPPN 219

Human   704 FVVQPNNQDGIY--GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN----- 761
            .....::.|.|.  |....|.|...|.|.|.:.||....|             ||.|..|     
  Fly   220 IDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNS-------------RIAINKNHIVNE 271

Human   762 ---SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAM------ITSHP---NTTIA-- 812
               .:|.|..:...|:|.|||.|||||...:||.:.::|..|.|      :...|   |.||.  
  Fly   272 WEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECF 336

Human   813 IKGHAKELNCTARGERPII---IRWEKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKLKPADRG 872
            .:.|...||...|||.|||   .:::...||..|  ...|:..|....:||:.:           
  Fly   337 TEAHPTSLNYWTRGEGPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGI----------- 390

Human   873 DSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYK 937
                :.|.|.|..||..|:|:|.|..||......|     .|.:..|.:    |.|         
  Fly   391 ----YKCVAKNPRGETDGIIRLYVSYPPTTASSGI-----YSTDTHWGE----NGI--------- 433

Human   938 NKSDSWDFKQSTRNI----SPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAP 998
            |.:.::....|||:|    ..|..|:|:                |:||.||....|         
  Fly   434 NNNYAYGGPDSTRSIYAQDKNTRYQSNL----------------NEIGLSEQKSFL--------- 473

Human   999 DGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGY 1034
                 |.|..|:.:..     .|.:.:.::...||:
  Fly   474 -----DKTQNPLLANG-----NANEADAESNGARGH 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DSCAML1XP_011541219.1 IG_like 43..119 CDD:214653
IGc2 43..110 CDD:197706
Ig 125..218 CDD:299845
IG_like 137..209 CDD:214653
I-set 245..323 CDD:254352
IGc2 252..313 CDD:197706
IGc2 340..401 CDD:197706
I-set 420..514 CDD:254352 12/63 (19%)
Ig 420..510 CDD:299845 11/59 (19%)
IGc2 531..589 CDD:197706 12/60 (20%)
IG_like 619..698 CDD:214653 12/81 (15%)
Ig 627..693 CDD:143165 10/65 (15%)
I-set 702..797 CDD:254352 30/104 (29%)
Ig7_DSCAM 719..797 CDD:143211 26/85 (31%)
I-set 803..896 CDD:254352 28/102 (27%)
Ig 815..903 CDD:299845 27/92 (29%)
FN3 899..993 CDD:238020 21/97 (22%)
FN3 1000..1097 CDD:238020 6/35 (17%)
fn3 1105..1191 CDD:278470
FN3 1203..1294 CDD:238020
IGc2 1318..1382 CDD:197706
FN3 1396..1486 CDD:238020
FN3 1500..1572 CDD:238020
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 31/181 (17%)
Ig 130..200 CDD:143165 21/151 (14%)
I-set 226..310 CDD:254352 29/96 (30%)
IGc2 233..298 CDD:197706 23/77 (30%)
Ig 313..410 CDD:299845 30/111 (27%)
IG_like 325..410 CDD:214653 28/99 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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