DRSC/TRiP Functional Genomics Resources

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Protein Alignment DSCAML1 and dpr4

DIOPT Version :9

Sequence 1:XP_011541219.1 Gene:DSCAML1 / 57453 HGNCID:14656 Length:2065 Species:Homo sapiens
Sequence 2:NP_001014616.2 Gene:dpr4 / 3346160 FlyBaseID:FBgn0053512 Length:323 Species:Drosophila melanogaster


Alignment Length:294 Identity:74/294 - (25%)
Similarity:108/294 - (36%) Gaps:86/294 - (29%)


- Green bases have known domain annotations that are detailed below.


Human   126 PYTVRVEDQRSMR------GNVAVFKCLIPSSVQEYVSVVSW--EKD----TVSIIP---EHRFF 175
            ||:....|..|.|      |..|:..|.:.:....   .|||  ::|    ||.|:.   :.||.
  Fly    41 PYSQPYFDNSSRREVTATVGQAALLHCRVRNLGDR---AVSWIRKRDLHILTVGILTYTNDQRFQ 102

Human   176 ITYHGG-----LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTGLARAADPLCLPDPAE 235
            ..:..|     |.||..|..|: .||.|    :.|.|.:.|.|.||:|. ::||           
  Fly   103 SLHSEGSDEWTLRISSPQPRDS-GTYEC----QVSTEPKISQGFRLNVV-VSRA----------- 150

Human   236 SIPTILDGFHSQEVWAGHTVELPCTASGYPIPA--IRWLKDGRPLPADSRW--------TKRITG 290
               .|| |.....:.:|..:.|.|.|...|:|.  |.|.|..|.:....|.        :.|.:.
  Fly   151 ---KIL-GNAELFIKSGSDINLTCLAMQSPVPPSFIYWYKGKRVMNYSQRGGINVITERSTRTSK 211

Human   291 LTISDLRTEDSGTYICEVTNT-------------------FGSAEATGILMVIDPLHVTLTPKKL 336
            |.|:.....|||.|.|..:::                   .|::.||    .:.||..|..|..|
  Fly   212 LLIAKATPADSGNYTCSPSSSDSASVVVHVINGEHPAAMQHGNSSAT----CLRPLSSTSVPFVL 272

Human   337 KTGIGSTVI-------LSCALTGSPEFTIRWYRN 363
            .|.:..||.       |:.....||::  ||:.|
  Fly   273 ATWMSMTVASVAWNSNLNINWNWSPDW--RWHWN 304

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DSCAML1XP_011541219.1 IG_like 43..119 CDD:214653
IGc2 43..110 CDD:197706
Ig 125..218 CDD:299845 32/111 (29%)
IG_like 137..209 CDD:214653 24/91 (26%)
I-set 245..323 CDD:254352 22/106 (21%)
IGc2 252..313 CDD:197706 19/89 (21%)
IGc2 340..401 CDD:197706 8/31 (26%)
I-set 420..514 CDD:254352
Ig 420..510 CDD:299845
IGc2 531..589 CDD:197706
IG_like 619..698 CDD:214653
Ig 627..693 CDD:143165
I-set 702..797 CDD:254352
Ig7_DSCAM 719..797 CDD:143211
I-set 803..896 CDD:254352
Ig 815..903 CDD:299845
FN3 899..993 CDD:238020
FN3 1000..1097 CDD:238020
fn3 1105..1191 CDD:278470
FN3 1203..1294 CDD:238020
IGc2 1318..1382 CDD:197706
FN3 1396..1486 CDD:238020
FN3 1500..1572 CDD:238020
dpr4NP_001014616.2 V-set 53..146 CDD:284989 28/100 (28%)
IG_like 53..145 CDD:214653 28/99 (28%)
ig 153..227 CDD:278476 20/74 (27%)
IG_like 161..>227 CDD:214653 18/65 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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