Protein Alignment PTGS1 and cd

DIOPT Version :9

• Sequence 1: NP_000953.2
• Gene: PTGS1 / 5742
• HGNCID: 9604
• Length: 599
• Species: Homo sapiens
• Sequence 2: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 124/593 - (20%)
• Similarity: 207/593 - (34%)
• Gaps: 171/593 - (28%)

Human    78 RNSLRPSPSFTHFLLTHGRWFWEFVNATFIR-----EMLMRLVLTVRS--------NLIPSPPTY 129
            |:|.....:||..|...|::....:.||.:.     |.:...|...|.        :::|..|.|
  Fly   276 RSSYETDSNFTVMLAVFGQFMDHDITATSLTTSQEGESIDCCVAATREQHPECYPVDILPDDPYY 340

Human   130 NSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTN 194
            ...:  ||..:|             .:..|.|.|..|    |..||                  |
  Fly   341 KQYN--ISCMNF-------------VRSAPAPTGRFG----PRMQL------------------N 368

Human   195 LMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDG- 258
            ...||                           :|...:||:..:||.|||.|.:|.|:..|.|.
  Fly   369 QATAF---------------------------IDASVVYGNLEQRQNQLRSFINGSLRMFVTDDG 406

Human   259 -EMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFG----------LLPGLMLYATLWLREHNRVC 312
             ::.|.|...|.       |........:|:..|.          ||..:.|   ||.|.||.:.
  Fly   407 RQLLPISSNPAD-------GCNRVQMTRLGKYCFESGDDRANENLLLTSMHL---LWARHHNYLA 461

Human   313 DLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY-------FLQLK--------FDP 362
            ..|:.::|.|.||:|:|..|.||..:...|...|::..|.|.       .|..|        :||
  Fly   462 RQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTYDP 526

Human   363 EL-------LFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYE-----QFLFNT-SMLV 414
            |:       .....|::.             |.|:|..|.:.....:.|     :.|||. |:..
  Fly   527 EVDPSIANCFAAAAFRFA-------------HTLLPGLFNISRDNSTPEAIELHKMLFNPFSLWA 578

Human   415 DYGVE-ALVDA-----------FSRQIAGRIGGGRNMDHHILHVAVDV----IRESREMRLQPFN 463
            ::|:: ||:.|           ||.::..::..|...|...| ..:|:    |:..|:..:..:.
  Fly   579 EHGIDHALMTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPL-CGLDLVSLNIQRGRDHGIPSYP 642

Human   464 EYRKRFGMKPYTSFQELVGEKEMAA--ELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGA 526
            .:|:...:....:::|:....:.|.  .:.::|.....::.|.|.|.|.....:|||..:..:.:
  Fly   643 VFRRHCRLPTVDTWEEMSQAIDNATLDSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVS 707

Human   527 PFSLKGLLGNPICSPEYW-----KPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQ 586
            ...|:..||:     .:|     .|..|.......|.|| :|..::|.|:.....|...|....:
  Fly   708 DQFLRLKLGD-----SHWYERKMGPQKFTKAQLAEIYKT-SLAAIICRNSDGITRVREHVMQRLR 766

Human   587 DDG-PAVE 593
            |.| |.|:
  Fly   767 DGGNPHVD 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGS1	NP_000953.2	EGF_CA	32..69	CDD:238011
		prostaglandin_endoperoxide_synthase	89..575	CDD:188648	114/561 (20%)
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	118/572 (21%)
		peroxinectin_like	364..750	CDD:188655	95/460 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810