Protein Alignment CG34367 and pitx1

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001035436.3
• Gene: pitx1 / 678598
• ZFINID: ZDB-GENE-060421-3623
• Length: 285
• Species: Danio rerio
• Alignment Length: 305
• Identity: 86/305 - (28%)
• Similarity: 127/305 - (41%)
• Gaps: 70/305 - (22%)

  Fly   140 LP-TASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQ 203
            || :||.|..|.: ||...:.|.....:|....:.|.:....||     ...||||.||:||..|
Zfish    11 LPRSASSTRETLE-NTSSESSDTEAAEKERSVEQRSDDGNADDP-----KKKKQRRQRTHFTSQQ 69

  Fly   204 LNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIA 268
            |.|||..|:...|||...|||::....|:||||:|||:|||||.||.|..........|..|..:
Zfish    70 LQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQMDLCKNSYLPQFS 134

  Fly   269 TPLEP-----------------CRVAP--------YVSLAALRSSSVPSHPAAATSSNPQAPGVS 308
            ..::|                 ...||        :.|::.|.|.|:.|.|::.:|       :|
Zfish   135 GLMQPYDDVYPTYTYNNWTNKGLTPAPLSTKNFTFFNSMSPLTSQSMFSAPSSISS-------MS 192

  Fly   309 GTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPA 373
            ..|..|        |:..|.:..:.:....:......  |..:|            |:::.|.|.
Zfish   193 MASGMG--------HSAVPGMPTTGLNNIGNLNGIGG--STINP------------AMSSSTCPY 235

  Fly   374 GLFSVPQYSINLAAFAAAHSKSSSIADLRMKAKKHSE--SLGLQA 416
            |. .|..||:      ...:.:||:|.||:|:|:|..  ..|||:
Zfish   236 GP-PVSPYSV------YRDTCNSSLATLRLKSKQHPSFGYSGLQS 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	31/55 (56%)
		OAR	392..410	CDD:461067	8/17 (47%)
pitx1	NP_001035436.3	COG5576	8..>126	CDD:227863	49/120 (41%)
		Homeodomain	59..115	CDD:459649	31/55 (56%)
		OAR	247..263	CDD:461067	7/15 (47%)