Protein Alignment CG34367 and PITX1

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: XP_047273274.1
• Gene: PITX1 / 5307
• HGNCID: 9004
• Length: 348
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 93/344 - (27%)
• Similarity: 131/344 - (38%)
• Gaps: 111/344 - (32%)

  Fly   102 YSLSPTLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTPKLAPDKPLLPE 166
            :.:.|..|.|                   :|.||:.....:||.:..||             |||
Human    59 HDMGPAFHLA-------------------RPADPREPLENSASESSDTE-------------LPE 91

  Fly   167 ECVSPEPSRNREH------CDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREEL 225
            :....||....:.      |...|......||||.||:||..||.|||..|:...|||..||||:
Human    92 KERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEI 156

  Fly   226 SQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCR--------------- 275
            :....|:|.||:|||:|||||.||.|.........|...|..:..::|..
Human   157 AVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAK 221

  Fly   276 -VAP----------YVSLAALRSSSV---PSHPAAATSSNPQAPG-VSGTSSSGKVVTVDSPHNH 325
             :||          :.|::.|.|.|:   ||..::.|..:...|| |.|..:||.       :|.
Human   222 SLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGL-------NNI 279

  Fly   326 NPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPAGLFSVPQYSINLAAFAA 390
            |             .:..::..||..|           .|...|| ||..:||.:.:.|
Human   280 N-------------NLTGSSLNSAMSP-----------GACPYGT-PASPYSVYRDTCN------ 313

  Fly   391 AHSKSSSIADLRMKAKKHS 409
                 ||:|.||:|:|:||
Human   314 -----SSLASLRLKSKQHS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	31/55 (56%)
		OAR	392..410	CDD:461067	9/18 (50%)
PITX1	XP_047273274.1	Homeodomain	124..180	CDD:459649	31/55 (56%)
		OAR	310..327	CDD:461067	8/27 (30%)