Protein Alignment CG34367 and VSX2

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_878314.1
• Gene: VSX2 / 338917
• HGNCID: 1975
• Length: 361
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 96/422 - (22%)
• Similarity: 144/422 - (34%)
• Gaps: 152/422 - (36%)

  Fly    30 GARLKKPTEVKNSIFINSISSGGSYADTCASGEESVDIDITDLSVSESNTILAIDPEPTEESHSQ 94
            |..|.||    .|..:...:|||:.| .|           |...:.|   ||.::.||
Human     6 GEALSKP----KSETVAKSTSGGAPA-RC-----------TGFGIQE---ILGLNKEP------- 44

  Fly    95 REEHVETYSLSPTLH-KAAVEPKPKNWLISED----------------------------LDVDS 130
                       |:.| :||::......|::..                            |:|.|
Human    45 -----------PSSHPRAALDGLAPGHLLAARSVLSPAGVGGMGLLGPGGLPGFYTQPTFLEVLS 98

  Fly   131 QPEDPKMSGLPTAS---ITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQ 192
            .|:...:..|..||   .|..|..|::..::.....:.:..::....|               |:
Human    99 DPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKR---------------KK 148

  Fly   193 RRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKG 257
            ||.||.||..||.|||:.|.|.||||.:.||.|:.:..|.|.|:||||||||||.||.|....:.
Human   149 RRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRS 213

  Fly   258 FLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSP 322
            .:                :|.|....|:...|:|
Human   214 SV----------------MAEYGLYGAMVRHSIP------------------------------- 231

  Fly   323 HNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPAG-------LFSVPQ 380
                  :..|.:|.....:..:.|     |.::.:......||..:|..|.|       |..:.|
Human   232 ------LPESILKSAKDGIMDSCA-----PWLLGMHKKSLEAAAESGRKPEGERQALPKLDKMEQ 285

  Fly   381 YSIN---LAAFAAAHSKSSSIADLRMKAKKHS 409
            ....   .||.:....:.:|||.||.||::||
Human   286 DERGPDAQAAISQEELRENSIAVLRAKAQEHS 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	33/55 (60%)
		OAR	392..410	CDD:461067	9/18 (50%)
VSX2	NP_878314.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		9/26 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..151		9/61 (15%)
		Homeodomain	153..205	CDD:459649	30/51 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..300		9/37 (24%)
		OAR	300..318	CDD:461067	9/18 (50%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	304..317		7/12 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..361		3/5 (60%)