Protein Alignment CG34367 and HOXB5

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 76/308 - (24%)
• Similarity: 116/308 - (37%)
• Gaps: 88/308 - (28%)

  Fly     4 LAQFVTKSFEFNLTNNSVHALFNSMTGARLKKPTEVKNSIFINSISSGGSYADTCA--SGEESVD 66
            ::.:...||.....|...:.|.|..:|:.|                 .|||.|..|  :|....:
Human     1 MSSYFVNSFSGRYPNGPDYQLLNYGSGSSL-----------------SGSYRDPAAMHTGSYGYN 48

  Fly    67 IDITDLSVSESNTILA----------IDPEPTEESHSQREEHVETYSLS-----PTLHKAAVEPK 116
            .:..||||:.|:...:          ..|.|.:|...:  :...:.|||     |..:..:...|
Human    49 YNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFR--QAASSCSLSSPESLPCTNGDSHGAK 111

  Fly   117 PKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVS--PEPSRNREH 179
            |.          .|.|.|...|...:|:.||..|.|.:.:        |||..|  ..||..|..
Human   112 PS----------ASSPSDQATSASSSANFTEIDEASASSE--------PEEAASQLSSPSLARAQ 158

  Fly   180 CDPLDTSLV----NTKQ-------------------RRSRTNFTLDQLNELERLFEETHYPDAFM 221
            .:|:.||..    .|.|                   :|:||.:|..|..|||:.|....|.....
Human   159 PEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRR 223

  Fly   222 REELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIAT 269
            |.|::..|.|||.::::||||||.|.:| :|::        :|..:||
Human   224 RIEIAHALCLSERQIKIWFQNRRMKWKK-DNKL--------KSMSLAT 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	23/55 (42%)
		OAR	392..410	CDD:461067
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	28/123 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		28/115 (24%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	23/55 (42%)