Protein Alignment CG34367 and HOXA4

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_002132.3
• Gene: HOXA4 / 3201
• HGNCID: 5105
• Length: 320
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 69/260 - (26%)
• Similarity: 100/260 - (38%)
• Gaps: 74/260 - (28%)

  Fly    85 PEPTE-------ESHSQREEHVETYSLSPTLHKAAVEP-KPKNWLISEDLDVDSQPEDPKMSGLP 141
            |:|.:       .:|.....||....|.|.|...||.| .|:.        .::.|..|   |:|
Human   114 PQPEQPPAQAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRR--------CEAAPATP---GVP 167

  Fly   142 T-ASITECTEDSNTPKLAPDKPLLPEECVSP--EPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQ 203
            . .|...|      |.|..||..|..:...|  .|...:.|...::.|....:.:||||.:|..|
Human   168 AGGSAPAC------PLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQ 226

  Fly   204 LNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIA 268
            :.|||:.|....|.....|.|::..|.|||.:|::||||||.|.:|.    ||
Human   227 VLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKD----HK------------ 275

  Fly   269 TPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNH---NPAIS 330
                            |.::.:.|..:|:.|:.|  ||.:.|         .|||.|   :|:.|
Human   276 ----------------LPNTKMRSSNSASASAGP--PGKAQT---------QSPHLHPHPHPSTS 313

  Fly   331  330
            Human   314  313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	25/55 (45%)
		OAR	392..410	CDD:461067
HOXA4	NP_002132.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..77
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..168		15/64 (23%)
		Antp-type hexapeptide	194..199		1/4 (25%)
		Homeodomain	216..272	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..320		16/84 (19%)