Protein Alignment CG34367 and ALX3

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 96/380 - (25%)
• Similarity: 138/380 - (36%)
• Gaps: 141/380 - (37%)

  Fly   113 VEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTPKL------APDKPLLPE----- 166
            |.|.|..::.|.|       |.|...|.|.|:..........|:|      .|.:|.|||
Human    11 VGPAPGPYVASGD-------EPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPP 68

  Fly   167 ----ECVSPEPSRNREH------------------------------------------C----- 180
                :.:.|.|:.|..|                                          |
Human    69 AKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLH 133

  Fly   181 --------DPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQ 237
                    |.::.:...:|:||:||.|:..||.|||::|::|||||.:.||:|:.|..|:|||||
Human   134 LPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQ 198

  Fly   238 VWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVP---SHP----- 294
            |||||||||.||.|..   |.:...|:|               ..||...|.:|   |||
Human   199 VWFQNRRAKWRKRERY---GKIQEGRNP---------------FTAAYDISVLPRTDSHPQLQNS 245

  Fly   295 --AAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISV 357
              |:..|.:|..|.:  .|..|......||::|    ...::..|....|.:||.
Human   246 LWASPGSGSPGGPCL--VSPEGIPSPCMSPYSH----PHGSVAGFMGVPAPSAAH---------- 294

  Fly   358 AAHQYAAAITNGTVPAGLFSVPQYSINLAAFAAAHS-----KSSSIADLRMKAKK 407
                           .|::|:..:...|...:...|     ||.|:..||:|.|:
Human   295 ---------------PGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	35/55 (64%)
		OAR	392..410	CDD:461067	8/21 (38%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		21/99 (21%)
		PRK12323	<13..131	CDD:481241	21/124 (17%)
		Homeodomain	154..210	CDD:459649	35/55 (64%)