Protein Alignment CG34367 and OTP

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_115485.1
• Gene: OTP / 23440
• HGNCID: 8518
• Length: 325
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 102/313 - (32%)
• Similarity: 138/313 - (44%)
• Gaps: 59/313 - (18%)

  Fly   125 DLDVDSQP---------EDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHC 180
            ||..:|.|         ||....|...||:....:|       |||...|:.  .|.||:..:..
Human    44 DLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKD-------PDKQPGPQG--GPNPSQAGQQQ 99

  Fly   181 DPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRA 245
            .       ..||:|.||.||..|||||||.|.:|||||.||||||:.|:||:|:|||||||||||
Human   100 G-------QQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRA 157

  Fly   246 KCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGT 310
            |.:|.:...:.....|:..|....|..|...|  .:.||:..|....|......:....||||
Human   158 KWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAA--AAAAAMGDSLCSFHANDTRWAAAAMPGVS-- 218

  Fly   311 SSSGKVVTVDSPHNHNPAISR-SAIKQFSSTVAAAA-----------AFSAFDPAIISVAAHQYA 363
                   .:..|    ||:.| .|:.|..|..:.||           :.:..:.|  .:.:|.|.
Human   219 -------QLPLP----PALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGA--GLQSHLYQ 270

  Fly   364 AAITNGTVPAGLFSVPQYSINLAAFAAAHS----KSSSIADLRMKAKKHSESL 412
            .|.. |.|||.|......|.:....::..|    :.:|||.||.||.:|:.|:
Human   271 PAFP-GMVPASLPGPSNVSGSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSM 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	40/55 (73%)
		OAR	392..410	CDD:461067	9/21 (43%)
OTP	NP_115485.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..112		22/83 (27%)
		Homeodomain	106..156	CDD:459649	36/49 (73%)
		OAR	303..320	CDD:461067	8/16 (50%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319		7/12 (58%)