Protein Alignment CG34367 and Shox2

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_038693.1
• Gene: Shox2 / 20429
• MGIID: 1201673
• Length: 331
• Species: Mus musculus
• Alignment Length: 273
• Identity: 124/273 - (45%)
• Similarity: 145/273 - (53%)
• Gaps: 66/273 - (24%)

  Fly   159 PDKPLLPEECVSPEPSRNREHCDPL-DTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMR 222
            |..|.|.|  ||||....::....: |......|||||||||||:|||||||||:||||||||||
Mouse   108 PGSPRLTE--VSPELKDRKDDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMR 170

  Fly   223 EELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRS 287
            |||||||||||||||||||||||||||.|||:|||.|:|:     |:..|.|||||||::.|||
Mouse   171 EELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGA-----ASQFEACRVAPYVNVGALR- 229

  Fly   288 SSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDP 352
              :|...                         ||..|..| :|.....|.....|.|.|.....|
Mouse   230 --MPFQQ-------------------------DSHCNVTP-LSFQVQAQLQLDSAVAHAHHHLHP 266

  Fly   353 AIISVAAHQYAAAITNGTVPAGLFSVPQYSINLAAFAA----------------AHSKSSSIADL 401
               .:|||          .|..:|..|.:.:.||..||                ..||:||||||
Mouse   267 ---HLAAH----------APYMMFPAPPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADL 318

  Fly   402 RMKAKKHSESLGL 414
            |:|||||:.:|||
Mouse   319 RLKAKKHAAALGL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	53/55 (96%)
		OAR	392..410	CDD:461067	14/17 (82%)
Shox2	NP_038693.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..140		9/33 (27%)
		Homeodomain	141..197	CDD:459649	53/55 (96%)
		OAR	311..327	CDD:461067	13/15 (87%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	313..326		11/12 (92%)