Protein Alignment CG34367 and Pitx2

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 268
• Identity: 76/268 - (28%)
• Similarity: 120/268 - (44%)
• Gaps: 38/268 - (14%)

  Fly   151 DSNTPKLA-PDKPL--LPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFE 212
            |:::|::| .||..  ..|:..:.:||:.:             :|||.||:||..||.|||..|:
Mouse    61 DTSSPEVAEKDKGQQGKNEDVGAEDPSKKK-------------RQRRQRTHFTSQQLQELEATFQ 112

  Fly   213 ETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVA 277
            ...|||...|||::....|:||||:|||:|||||.||.|.............|.....::|
Mouse   113 RNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQP---- 173

  Fly   278 PYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVA 342
                    .....|.:    :.:|..|.|::..|.|.|.....:..|.||..|:|.....:|..:
Mouse   174 --------YDDMYPGY----SYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISS 226

  Fly   343 AAAAFSAFDPAIISVAAHQYAAA--ITNGTVPAGLFSVP----QYSINLAAFAAAHSKSSSIADL 401
            .:.:.|....|:..|......:.  :.|.:.|:...:||    .|:.....:....:.:||:|.|
Mouse   227 MSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASL 291

  Fly   402 RMKAKKHS 409
            |:|||:||
Mouse   292 RLKAKQHS 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	31/55 (56%)
		OAR	392..410	CDD:461067	10/18 (56%)
Pitx2	NP_001035967.1	Homeodomain	93..149	CDD:459649	31/55 (56%)
		OAR	282..299	CDD:461067	8/16 (50%)