DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG34367 and DLX4

DIOPT Version :10

Sequence 1:NP_001097140.1 Gene:CG34367 / 5740879 FlyBaseID:FBgn0085396 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_612138.1 Gene:DLX4 / 1748 HGNCID:2917 Length:240 Species:Homo sapiens


Alignment Length:182 Identity:55/182 - (30%)
Similarity:82/182 - (45%) Gaps:33/182 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 LSPTLHKAAVEP-----KPKNWLISEDLDVDSQPEDPKMSGLPTASITE--CTEDSNTPKLAPD- 160
            ||||   .|..|     :|...|:|......:.|.|..:|....|::::  |....:..:|..| 
Human    35 LSPT---TAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADS 96

  Fly   161 -KPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREE 224
             ||.|     |||||..|.....       .|.|:.||.::..||..|.:.|:.|.|.....|.:
Human    97 EKPRL-----SPEPSERRPQAPA-------KKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQ 149

  Fly   225 LSQRLGLSEARVQVWFQNRRAKCRKHENQMHKG---------FLVGSRSPPI 267
            |:.:|||::.:|::||||:|:|.:|...|...|         |.|...|||:
Human   150 LAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPL 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34367NP_001097140.1 Homeodomain 193..249 CDD:459649 21/55 (38%)
OAR 392..410 CDD:461067
DLX4NP_612138.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 80..120 14/51 (27%)
Homeodomain 118..174 CDD:459649 21/55 (38%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.