Protein Alignment CG34367 and Hhex

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 181
• Identity: 51/181 - (28%)
• Similarity: 70/181 - (38%)
• Gaps: 35/181 - (19%)

  Fly    98 HVETYSLSPTLHKAAVEPKPKNWLISEDLDVDS------------QPEDPKMSGLPTASITECTE 150
            |...:.:...|.:....|.|...|.|.:....|            .|..|..|..|.|::.....
Mouse    29 HPTPFYIDDILGRGPAAPTPTPTLPSPNSSFTSLVSSYRTPVYEPTPVHPAFSHHPAAALAAAYG 93

  Fly   151 DSNTPKLAPDKPLLPEECVSPEPSRNREHC----DPLDTSLVNT--------KQRRSRTNFTLDQ 203
            .|..     ..||.|    .|....:..|.    |||...|:.:        |::..:..|:.||
Mouse    94 PSGF-----GGPLYP----FPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQ 149

  Fly   204 LNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR--KHEN 252
            ..|||:.||...|.....|:.|::.|.|||.:|:.||||||||.|  |.||
Mouse   150 TVELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQEN 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	25/57 (44%)
		OAR	392..410	CDD:461067
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		22/117 (19%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		28/63 (44%)
		Homeodomain	143..195	CDD:459649	24/51 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		3/6 (50%)