Protein Alignment CG34367 and Cdx1

DIOPT Version :10

• Sequence 1: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 230
• Identity: 61/230 - (26%)
• Similarity: 87/230 - (37%)
• Gaps: 30/230 - (13%)

  Fly    85 PEPTEES--HSQREEHVETYSLSPTLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITE 147
            |.||..:  .:.:::....|...||  .:|..|.|..:....|......|..|. .|:...|:
Mouse    57 PPPTWAAPFPAPKDDWAAAYGPGPT--ASAASPAPLAFGPPPDFSPVPAPPGPG-PGILAQSL-- 116

  Fly   148 CTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFE 212
                 ..|. ||..|..|.........|:........:....||. :.|..:|..|..|||:.|.
Mouse   117 -----GAPG-APSSPGAPRRTPYEWMRRSVAAAGGGGSGKTRTKD-KYRVVYTDHQRLELEKEFH 174

  Fly   213 ETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVA 277
            .:.|.....:.||:..|||:|.:|::||||||||.||          |..:......||.|.::.
Mouse   175 YSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERK----------VNKKKQQQQQPLPPTQLP 229

  Fly   278 PYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSS 312
                 ..|..:..||.|... |..|...|:.||.|
Mouse   230 -----LPLDGTPTPSGPPLG-SLCPTNAGLLGTPS 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	23/55 (42%)
		OAR	392..410	CDD:461067
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		20/105 (19%)
		Caudal_act	13..140	CDD:461413	20/93 (22%)
		Homeodomain	156..211	CDD:459649	23/54 (43%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		7/20 (35%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		6/10 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		16/66 (24%)